Carbohydrate vaccines: developing sweet solutions to sticky situations?
Carbohydrate vaccines: developing sweet solutions to sticky situations?
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碳水化合物疫苗:为粘性情况开发甜蜜的解决方案吗?
DOI:
10.1038/nrd3012
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发表时间:
2010-04
期刊:
影响因子:
--
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中科院分区:
文献类型:
--
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The realm of carbohydrate vaccines has expanded far beyond the capsular polysaccharides of bacterial pathogens to include a diverse collection of targets representing nearly every biological kingdom. Recent technological advances in glycobiology and glycochemistry are paving the way for a new era in carbohydrate vaccine design enabling greater efficiency in the identification, synthesis and evaluation of unique glycan epitopes found on a plethora of pathogens and malignant cells. This article reviews the progress being made in addressing challenges posed by targeting the surface carbohydrates of bacteria, protozoa, helminths, viruses, fungi and cancer for vaccine purposes.
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影响因子:
6.4
作者:
Ahmed, A;Li, JP;Szu, SC
通讯作者:
Szu, SC
影响因子:
4.3
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Buskas, T;Li, YH;Boons, GJ
通讯作者:
Boons, GJ
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64.5
作者:
Cobb, BA;Wang, O;Kasper, DL
通讯作者:
Kasper, DL
影响因子:
3
作者:
Braun, DP;Crist, KA;Parker, J
通讯作者:
Parker, J
影响因子:
1.8
作者:
CARVER, JP
通讯作者:
CARVER, JP