Three clusters of bovine kobuvirus isolated in Korea, 2008-2010.

Three clusters of bovine kobuvirus isolated in Korea, 2008-2010.
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2008 - 2010年在韩国隔离的三个牛毛无病毒簇。

DOI:
10.1007/s11262-011-0593-9
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发表时间:
2011-06
期刊:
影响因子:
1.6
通讯作者:
An DJ
An DJ
中科院分区:
医学4区
文献类型:
--
作者:
Jeoung HY;Lim JA;Jeong W;Oem JK;An DJ

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2008-2010年期间,从韩国农场确诊或疑似腹泻的牛身上采集了粪便样本(n=1 107)。在这些样本中,有37个样本的牛柯布病毒检测呈阳性。37个阳性样本来自32头出现腹泻症状的牛和5头非腹泻牛。大多数病毒阳性粪便样本来自1个月龄以下的小牛(n=425)。在感染牛柯布病毒的37头牛中,有9头牛被确认与其他病毒混合感染,包括牛轮状病毒(n=3)、牛冠状病毒(n=1)、牛病毒性腹泻病毒(n=1)以及牛冠状病毒和牛病毒性腹泻病毒(n=4)。邻接树将36株韩国柯布病毒毒株(Kb8株除外)聚为三类(G1、G3和G4),而来自泰国和日本的毒株(U1株除外)被包括在G2簇中。结果表明,朝鲜牛柯布病毒具有不同的谱系,不同的疾病状态和物种。本文的在线版本(doi:10.1007/s11262-0110593-9)包含补充材料,授权用户可以使用。
Fecal samples (n = 107) were collected from cattle with ascertained or suspected diarrheal disease on Korean farms during 2008–2010. Of these, 37 samples tested positive for bovine kobuvirus. The 37 positive samples came from 32 cattle that exhibited diarrhea and five cattle that were non-diarrhetic. The majority of the virus-positive feces samples were from calves under 1 month of age (n = 25). Nine of the 37 cattle infected with bovine kobuvirus were confirmed to have a co-infection with other viruses including bovine rotavirus (n = 3), bovine coronavirus (n = 1), bovine viral diarrhea virus (n = 1), and both bovine coronavirus and bovine viral diarrhea virus (n = 4). A neighbor-joining tree grouped 36 of the Korean kobuvirus strains (with the exception of the KB8 strain) into three clusters (G1, G3, and G4), while strains derived from Thailand and Japan (except the U1 strain) were included in the G2 cluster. The results indicated that Korean bovine kobuvirus has diverse lineages regardless of disease status and species. The online version of this article (doi:10.1007/s11262-011-0593-9) contains supplementary material, which is available to authorized users.
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