Site-directed photochemical disruption of the actin cytoskeleton by actin-binding Rose Bengal-conjugates.
Site-directed photochemical disruption of the actin cytoskeleton by actin-binding Rose Bengal-conjugates.
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通过与肌动蛋白结合的玫瑰红缀合物对肌动蛋白细胞骨架进行定点光化学破坏。
DOI:
10.1016/s1011-1344(02)00382-2
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发表时间:
2002
期刊:
影响因子:
--
通讯作者:
Berrios,Miguel
中科院分区:
文献类型:
--
作者:
Conlon,KimberlyA;Rosenquist,Thomas;Berrios,Miguel
The in situ light-induced, non-enzymatic digestion of cytoskeletal actin by a xanthene dye conjugated to heavy meromyosin, anti-actin antibodies and/or anti-myosin antibodies is reported. The dye Rose Bengal was conjugated to either anti-actin antibodies, anti-myosin antibodies or heavy meromyosin. Under our experimental conditions, visible light induced the non-enzymatic breakdown of cytoskeletal actin when mammalian tissue culture cells were probed either with Rose Bengal-conjugated anti-actin and/or anti-myosin antibodies. Similar results were obtained when tissue culture cells were probed with Rose Bengal-conjugated heavy meromyosin before irradiation with visible light. The in situ photochemical reaction depended on the presence of actin-binding Rose Bengal-conjugates.
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DOI:
10.1016/s1011-1344(01)00241-x
发表时间:
2001-12
期刊:
Journal of photochemistry and photobiology. B, Biology
影响因子:
--
作者:
K. Conlon;M. Berrios
通讯作者:
K. Conlon;M. Berrios
影响因子:
1.1
作者:
Kimberly A. Conion;A. Grollman;M. Berrios
通讯作者:
M. Berrios
影响因子:
--
作者:
P. Fisher;M. Berrios
通讯作者:
M. Berrios
DOI:
10.1016/s0167-4838(98)00145-9
发表时间:
1998-09-08
期刊:
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY
影响因子:
--
作者:
Buranaprapuk, A;Leach, SP;Bocarsly, JR
通讯作者:
Bocarsly, JR
DOI:
--
发表时间:
1977
影响因子:
11.1
作者:
M. Heggeness;K. Wang;S. Singer
通讯作者:
S. Singer