Chemoprevention for the Populations of Malaria Endemic Africa.

Chemoprevention for the Populations of Malaria Endemic Africa.
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DOI:
10.3390/diseases10040101
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发表时间:
2022-11-08
期刊:
Diseases (Basel, Switzerland)
影响因子:
--
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其他
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几个世纪以来,药物一直被用来预防疟疾,但直到最近,它们才被大规模用于在撒哈拉以南非洲疟疾流行区的常住人口中预防疟疾。本文讨论了撒哈拉以南非洲在采用化学预防战略方面犹豫不决的一些原因,为什么近年来克服了这种犹豫不决的原因,以及世界卫生组织现在确定的目标群体范围,即那些最能从化学预防中受益的群体。采取精心定向的化学预防战略可能有助于扭转撒哈拉以南非洲最近疟疾下降的停滞局面,过去20年里这种情况一直在发生。
Drugs have been used to prevent malaria for centuries, but only recently have they been used on a large scale to prevent malaria in the resident population of malaria endemic areas in sub-Saharan Africa. This paper discusses some of the reasons for the hesitancy in adoption of chemopreventive strategies in sub-Saharan Africa, reasons why this hesitancy has been overcome in recent years and the range of target groups now identified by the World Health Organization as those who can benefit most from chemoprevention. Adoption of carefully targeted chemopreventive strategies could help reverse the recent stagnation in the decline in malaria in sub-Saharan Africa that had been taking place during the previous two decades.
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