libsbmljs-Enabling web-based SBML tools.
libsbmljs-Enabling web-based SBML tools.
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DOI:
10.1016/j.biosystems.2020.104150
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发表时间:
2020-07
期刊:
影响因子:
--
通讯作者:
Sauro HM
中科院分区:
文献类型:
--
作者:
Medley JK;Hellerstein J;Sauro HM
The SBML standard is used in a number of online repositories for storing systems biology models, yet there is currently no Web–capable JavaScript library that can read and write the SBML format. This is a severe limitation since the Web has become a universal means of software distribution, and the graphical capabilities of modern web browsers offer a powerful means for building rich, interactive applications. Also, there is a growing developer population specialized in web technologies that is poised to take advantage of the universality of the web to build the next generation of tools in systems biology and other fields. However, current solutions require server–side processing in order to support existing standards in modeling. We present libsbmljs, a JavaScript / WebAssembly library for Node.js and the Web with full support for all SBML extensions. Our library is an enabling technology for online SBML editors, model–building tools, and web–based simulators, and runs entirely in the browser without the need for any dedicated server resources. We provide NPM packages, an extensive set of examples, JavaScript API documentation, and an online demo that allows users to read and validate the SBML content of any model in the BioModels and BiGG databases. We also provide instructions and scripts to allow users to build a copy of libsbmljs against any libSBML version. Although our library supports all existing SBML extensions, we cover how to add additional extensions to the wrapper, should any arise in the future. To demonstrate the utility of this implementation, we also provide a demo at https://libsbmljsdemo.github.io/ with a proof–of–concept SBML simulator that supports ODE and stochastic simulations for SBML core models.
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DOI:
10.1093/bioinformatics/btv341
发表时间:
2015-10-15
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Rodriguez N;Thomas A;Watanabe L;Vazirabad IY;Kofia V;Gómez HF;Mittag F;Matthes J;Rudolph J;Wrzodek F;Netz E;Diamantikos A;Eichner J;Keller R;Wrzodek C;Fröhlich S;Lewis NE;Myers CJ;Le Novère N;Palsson BØ;Hucka M;Dräger A
通讯作者:
Dräger A
影响因子:
4.3
作者:
King ZA;Dräger A;Ebrahim A;Sonnenschein N;Lewis NE;Palsson BO
通讯作者:
Palsson BO
影响因子:
1.9
作者:
Olivier, Brett G.;Bergmann, Frank T.
通讯作者:
Bergmann, Frank T.
影响因子:
5.8
作者:
Olivier, BG;Snoep, JL
通讯作者:
Snoep, JL
影响因子:
5.8
作者:
Bornstein, Benjamin J.;Keating, Sarah M.;Hucka, Michael
通讯作者:
Hucka, Michael