2D free-breathing dual navigator-gated cardiac function validated against the 2D breath-hold acquisition.

2D free-breathing dual navigator-gated cardiac function validated against the 2D breath-hold acquisition.
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2D自由呼吸双导航器门控心脏功能通过2D呼吸持有的习惯验证。

DOI:
10.1002/jmri.21417
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发表时间:
2008-09
影响因子:
4.4
通讯作者:
Manning, Warren J.
Manning, Warren J.
中科院分区:
医学2区
文献类型:
--
作者:
Peters, Dana C.;Nezafat, Reza;Eggers, Holger;Stehning, Christian;Manning, Warren J.

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开发和验证自由呼吸心脏影像采集,有可能简化心脏MR研究,提供注册切片并提高空间分辨率。开发了一种2D自由呼吸(FB)导航门控心功能影像采集技术,使用两个导航器(一个放置在QRS之前,另一个放置在QRS复合体后500 ms,收缩期后)提供完整的收缩运动补偿评估,没有舒张末期损失。研究了11个对象。二维FB方法提供的结果在视觉和定量上与二维屏气(BH)方法相似。自由呼吸法测量的容积与标准2D BH仪测量的容积比较,舒张末期容积、收缩末期容积、左室质量和射血分数的平均偏差为±2个标准差,分别为1.0 ml±13.7 ml、1.1 ml±7.6 ml、3.0 g±18.8 g和0.3%±2.5%。在4个(36%)的BH研究中发现了切片错配,但在FB研究中没有发现(0%)。在切片配准错误的受试者中,左室容积测量的不一致性更大(舒张末期质量P<0.05)。自由呼吸影像采集的定性和定量结果与改进的切片配准的二维屏气方法相似。
To develop and validate a free-breathing cardiac cine acquisition, with potential to simplify cardiac MR studies, provide registered slices and increase spatial resolution. A 2D free-breathing (FB) navigator-gated cine radial acquisition for cardiac function was developed which used two navigators (one placed prior to the QRS, and another 500 ms after the QRS complex, after systole) to provide complete motion-compensated assessment of systole, without loss of end-diastole. Eleven subjects were studied. The 2D FB method provided results visually and quantitatively similar to the 2D breath-hold (BH) methods. Comparison of volumes measured with the free-breathing to those measured by standard 2D BH cine resulted in mean bias ± 2 standard deviations of 1.0 ml ± 13.7 ml, 1.1 ml ± 7.6 ml, 3.0 g ± 18.8 g, and 0.3 %± 2.5%, for end-diastolic volume, end-systolic volume, and left-ventricular mass, and ejection fraction, respectively. Slice misregistration was identified in 4 (36%) of the BH studies, but none (0%) of the FB studies. In subjects with slice misregistration, there was greater discordance in LV volume measurements (P<0.05 for end-diastolic mass). The free-breathing cine acquisition provided results qualitatively and quantitatively similar to 2D breath-hold methods with improved slice registration.
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