Puberty Initiates Cascading Relationships Between Neurodevelopmental, Social, and Internalizing Processes Across Adolescence.

Puberty Initiates Cascading Relationships Between Neurodevelopmental, Social, and Internalizing Processes Across Adolescence.
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青春期启动了整个青春期神经发育、社交和内化过程之间的级联关系。

DOI:
10.1016/j.biopsych.2020.09.002
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发表时间:
2021-01-15
影响因子:
10.6
通讯作者:
Allen NB
Allen NB
中科院分区:
医学1区
文献类型:
--
作者:
Pfeifer JH;Allen NB

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青春期是一个戏剧性的发展过渡时期--从与青春期有关的荷尔蒙、身体和大脑的变化到日益复杂的社交世界。许多精神障碍的发病同时增加,促使人们寻找关键的发育过程,这些过程推动了这一时期精神病理学风险的变化。与青春期发育有关的荷尔蒙激增和随之而来的身体成熟被认为影响大脑发育、社会认知和同伴关系的多个方面;其中每一个方面也表明与情绪和焦虑症的风险有关。这些与青春期有关的影响可能与其他对大脑成熟的非青春期影响结合在一起,改变青少年的社会认知和经历,进而通过交易过程继续塑造心理健康和大脑发育。在这篇综述中,我们专注于青春期期间的青春期、神经和社会变化,这些变化已知或被认为与青春期出现的障碍有关,特别是抑郁、焦虑和故意的自残(非自杀性自残)。我们提出了一个理论模型,其中社会过程(包括社会认知和同伴关系)对于理解青春期发育驱动神经和心理变化的方式至关重要,这些变化会产生潜在的心理健康脆弱性,特别是(但不只是)在青春期女孩中。
Adolescence is a period of dramatic developmental transitions -- from puberty-related changes in hormones, bodies, and brains to an increasingly complex social world. The concurrent increase in the onset of many mental disorders has prompted the search for key developmental processes that drive changes in risk for psychopathology during this period of life. Hormonal surges and consequent physical maturation linked to pubertal development in adolescence are believed to impact multiple aspects of brain development, social cognition, and peer relations; each of which have also demonstrated associations with risk for mood and anxiety disorders. These puberty-related effects may combine with other non-pubertal influences on brain maturation to transform adolescents’ social perception and experiences, which in turn continue to shape both mental health and brain development through transactional processes. In this review, we focus on pubertal, neural, and social changes across the duration of adolescence that are known or believed to be related to adolescent-emergent disorders, specifically depression, anxiety, and deliberate self-harm (non-suicidal self-injury). We propose a theoretical model in which social processes (both social cognition and peer relations) are critical to understanding the way in which pubertal development drives neural and psychological changes that produce potential mental health vulnerabilities, particularly (but not exclusively) in adolescent girls.
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