Challenges of Developing Novel Vaccines With Particular Global Health Importance.
Challenges of Developing Novel Vaccines With Particular Global Health Importance.
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DOI：
10.3389/fimmu.2020.517290
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发表时间：
2020
影响因子：
7.3
通讯作者：
Heaton PM
中科院分区：
文献类型：
--
作者：
Heaton PM
在资源匮乏的环境中，十大主要死亡原因中有六个可能通过接种疫苗得到预防。由于流行病原体的生物学复杂性和开发任何疫苗所固有的挑战，为这些人群中的个人开发疫苗是困难的。本综述讨论了这些挑战和解决这些挑战的有希望的进展，并强调了针对几种感兴趣的病原体的疫苗开发的最新进展。
Six of the top ten leading causes of death in low resource settings could potentially be prevented by vaccination. Development of vaccines for individuals in these populations is difficult because of the biological complexity of the prevalent pathogens and the challenges inherent to development of any vaccine. This review discusses those challenges and promising advances to address them and highlights recent progress in development of vaccines against several pathogens of interest.
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DOI：
10.1056/nejmoa1714021
发表时间：
2018-07-12
期刊：
The New England journal of medicine
影响因子：
--
作者：
Nemes E;Geldenhuys H;Rozot V;Rutkowski KT;Ratangee F;Bilek N;Mabwe S;Makhethe L;Erasmus M;Toefy A;Mulenga H;Hanekom WA;Self SG;Bekker LG;Ryall R;Gurunathan S;DiazGranados CA;Andersen P;Kromann I;Evans T;Ellis RD;Landry B;Hokey DA;Hopkins R;Ginsberg AM;Scriba TJ;Hatherill M;C-040-404 Study Team
通讯作者：
C-040-404 Study Team
影响因子：
8.8
作者：
Ryg-Cornejo, Victoria;Ioannidis, Lisa Julia;Hansen, Diana Silvia
通讯作者：
Hansen, Diana Silvia
DOI：
10.1016/j.tube.2016.09.004
发表时间：
2016-12
期刊：
Tuberculosis (Edinburgh, Scotland)
影响因子：
--
作者：
Sharpe S;White A;Sarfas C;Sibley L;Gleeson F;McIntyre A;Basaraba R;Clark S;Hall G;Rayner E;Williams A;Marsh PD;Dennis M
通讯作者：
Dennis M
DOI：
10.1016/s0140-6736(17)30938-8
发表时间：
2017-09-02
期刊：
Lancet (London, England)
影响因子：
--
作者：
Shi T;McAllister DA;O'Brien KL;Simoes EAF;Madhi SA;Gessner BD;Polack FP;Balsells E;Acacio S;Aguayo C;Alassani I;Ali A;Antonio M;Awasthi S;Awori JO;Azziz-Baumgartner E;Baggett HC;Baillie VL;Balmaseda A;Barahona A;Basnet S;Bassat Q;Basualdo W;Bigogo G;Bont L;Breiman RF;Brooks WA;Broor S;Bruce N;Bruden D;Buchy P;Campbell S;Carosone-Link P;Chadha M;Chipeta J;Chou M;Clara W;Cohen C;de Cuellar E;Dang DA;Dash-Yandag B;Deloria-Knoll M;Dherani M;Eap T;Ebruke BE;Echavarria M;de Freitas Lázaro Emediato CC;Fasce RA;Feikin DR;Feng L;Gentile A;Gordon A;Goswami D;Goyet S;Groome M;Halasa N;Hirve S;Homaira N;Howie SRC;Jara J;Jroundi I;Kartasasmita CB;Khuri-Bulos N;Kotloff KL;Krishnan A;Libster R;Lopez O;Lucero MG;Lucion F;Lupisan SP;Marcone DN;McCracken JP;Mejia M;Moisi JC;Montgomery JM;Moore DP;Moraleda C;Moyes J;Munywoki P;Mutyara K;Nicol MP;Nokes DJ;Nymadawa P;da Costa Oliveira MT;Oshitani H;Pandey N;Paranhos-Baccalà G;Phillips LN;Picot VS;Rahman M;Rakoto-Andrianarivelo M;Rasmussen ZA;Rath BA;Robinson A;Romero C;Russomando G;Salimi V;Sawatwong P;Scheltema N;Schweiger B;Scott JAG;Seidenberg P;Shen K;Singleton R;Sotomayor V;Strand TA;Sutanto A;Sylla M;Tapia MD;Thamthitiwat S;Thomas ED;Tokarz R;Turner C;Venter M;Waicharoen S;Wang J;Watthanaworawit W;Yoshida LM;Yu H;Zar HJ;Campbell H;Nair H;RSV Global Epidemiology Network
通讯作者：
RSV Global Epidemiology Network
HIV-1 疫苗功效试验的免疫相关分析。
DOI：
10.1056/nejmoa1113425
发表时间：
2012-04-05
期刊：
The New England journal of medicine
影响因子：
--
作者：
Haynes BF;Gilbert PB;McElrath MJ;Zolla-Pazner S;Tomaras GD;Alam SM;Evans DT;Montefiori DC;Karnasuta C;Sutthent R;Liao HX;DeVico AL;Lewis GK;Williams C;Pinter A;Fong Y;Janes H;DeCamp A;Huang Y;Rao M;Billings E;Karasavvas N;Robb ML;Ngauy V;de Souza MS;Paris R;Ferrari G;Bailer RT;Soderberg KA;Andrews C;Berman PW;Frahm N;De Rosa SC;Alpert MD;Yates NL;Shen X;Koup RA;Pitisuttithum P;Kaewkungwal J;Nitayaphan S;Rerks-Ngarm S;Michael NL;Kim JH
通讯作者：
Kim JH