The effects of parity and litter size on bone metabolic activity in pregnant and lactating sows
The effects of parity and litter size on bone metabolic activity in pregnant and lactating sows
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胎次和产仔数对妊娠和哺乳母猪骨代谢活性的影响
DOI：
10.1111/jpn.12958
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发表时间：
2018
影响因子：
2.7
通讯作者：
Hood, Wendy R.
中科院分区：
文献类型：
--
作者：
Schmidt, Christina M.;Chiba, Lee I.;Hood, Wendy R.
在妊娠和哺乳期间，雌性哺乳动物经常调动内源性营养储备，以满足后代生产的资源需求。这些动员的储存物包括钙、磷和其他矿物质，这些矿物质从母体骨中被再吸收，以促进后代骨的快速矿化。骨矿物质被再吸收的程度取决于从饮食中摄入的矿物质总量，但也取决于后代的竞争需求和女性必须维持以支持自我维持的最低骨密度水平。女性可以调动的最大骨量无疑取决于各种母性特征，包括年龄和生殖经验（即，平价）。我们评估了约克郡母猪在整个妊娠期和哺乳期内母体骨代谢活性生物标志物（总脱氧吡啶啉[tDPD]和骨钙素[OC]）的血清浓度变化及其与繁殖产量和产次的关系。窝仔数不影响骨代谢;然而，与当前繁殖前至少产3窝的母猪相比，几乎没有或没有繁殖经验的母猪中tDPD和OC的血清浓度显著较高。这表明满足后代矿物质需求的能力或生理策略发生了变化，这些需求是后天获得的或与生殖经验有关。
During gestation and lactation, female mammals often mobilize endogenous nutrient reserves to meet the resource demands of offspring production. These mobilized stores include calcium, phosphorous and other minerals that are resorbed from maternal bone to facilitate rapid mineralization of offspring bones. The extent to which bone mineral is resorbed is governed by the total amount of mineral taken in from the diet, but also by the competing demands of offspring and the minimum level of bone density that a female must sustain to support self‐maintenance. The maximum amount of bone that a female may mobilize is undoubtedly dependent a variety of maternal traits, including age and reproductive experience (i.e., parity). We evaluated changes in serum concentrations of biomarkers of metabolic activity (total deoxypyridinoline [tDPD] and osteocalcin [OC]) of maternal bone and its relationship to reproductive output and parity throughout pregnancy and lactation in Yorkshire sows. Litter size did not affect bone metabolism; however, serum concentrations of both tDPD and OC were significantly higher in sows with little or no reproductive experience when compared to sows that had produced at least 3 litters prior to the current reproductive bout. This suggests a shift in ability or physiological strategy to meet offspring mineral demands that is acquired or associated with reproductive experience.
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哺乳仔鼠数量和膳食钙对哺乳大鼠股骨骨矿物质含量和力学性能的影响。
DOI：
--
发表时间：
1988
期刊：
Bone and mineral
影响因子：
--
作者：
Peng,TC;Garner,SC;Kusy,RP;Hirsch,PF
通讯作者：
Hirsch,PF
与第一次哺乳期相比，第二次妊娠和哺乳期奶山羊和绵羊的骨代谢。
DOI：
10.1111/j.1439-0396.2007.00695.x
发表时间：
2007
影响因子：
2.7
作者：
Annette Liesegang;Juha Risteli;Marcel Wanner
通讯作者：
Marcel Wanner
DOI：
10.2460/javma.235.6.734
发表时间：
2009-09-15
影响因子：
1.9
作者：
Anil, Sukumarannair S.;Anil, Leena;Deen, John
通讯作者：
Deen, John
DOI：
--
发表时间：
1998
期刊：
影响因子：
--
作者：
M. Tannerfeldt;A. Angerbjörn
通讯作者：
A. Angerbjörn
繁殖周期和年龄对母猪钙磷代谢和骨完整性的影响。
影响因子：
3.3
作者：
M. Giesemann;A. Lewis;P. S. Miller;M. Akhter
通讯作者：
M. Akhter