Transcriptional regulation and its misregulation in disease.
Transcriptional regulation and its misregulation in disease.
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DOI:
10.1016/j.cell.2013.02.014
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发表时间:
2013-03-14
期刊:
影响因子:
64.5
通讯作者:
Young RA
中科院分区:
文献类型:
--
作者:
Lee TI;Young RA
The gene expression programs that establish and maintain specific cell states in humans are controlled by thousands of transcription factors, cofactors and chromatin regulators. Misregulation of these gene expression programs can cause a broad range of diseases. Here we review recent advances in our understanding of transcriptional regulation and discuss how these have provided new insights into transcriptional misregulation in disease.
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影响因子:
64.5
作者:
Bai X;Kim J;Yang Z;Jurynec MJ;Akie TE;Lee J;LeBlanc J;Sessa A;Jiang H;DiBiase A;Zhou Y;Grunwald DJ;Lin S;Cantor AB;Orkin SH;Zon LI
通讯作者:
Zon LI
影响因子:
11.2
作者:
Aguilo F;Zhou MM;Walsh MJ
通讯作者:
Walsh MJ
影响因子:
9.8
作者:
Bown, Matthew J.;Jones, Gregory T.;Samani, Nilesh J.
通讯作者:
Samani, Nilesh J.
影响因子:
16
作者:
Barboric, M;Nissen, RM;Peterlin, BM
通讯作者:
Peterlin, BM
DOI:
10.1126/science.1191078
发表时间:
2010-10-29
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Bonasio R;Tu S;Reinberg D
通讯作者:
Reinberg D