Housing status and the health of people living with HIV/AIDS.

Housing status and the health of people living with HIV/AIDS.
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DOI:
10.1007/s11904-012-0137-5
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发表时间:
2012-12
影响因子:
4.6
通讯作者:
Wood, Evan
Wood, Evan
中科院分区:
医学2区
文献类型:
--
作者:
Milloy, M. -J.;Marshall, Brandon D. L.;Montaner, Julio;Wood, Evan

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无家可归或生活在边缘条件下的个人感染艾滋病毒的负担增加。现有研究表明,在资源丰富的环境中,艾滋病毒/艾滋病大流行日益集中在弱势和边缘化人群中,包括无家可归/居住在边缘的个人,他们尚未从高效抗逆转录病毒疗法(HAART)的最新进展中充分受益。我们回顾了调查劣质住房与艾滋病毒/艾滋病患者的健康状况、HAART的可获得性和依从性以及HIV治疗结果之间关系的科学证据。研究表明,无家可归/居住在边远地区的情况在PLWHA中很常见,这与获得较差的HAART和次优治疗结果有关。在无家可归者/边缘居住的PLWHA中,较差的HAART获得/遵守或治疗结果的决定因素包括抑郁、非法药物使用和药物保险状况。未来的研究应考虑HAART获得和HV治疗结果的可能的社会和结构层面的决定因素,这些因素已被证明增加了无家可归者/边缘住房的人感染艾滋病毒的易感性。有证据表明,符合适当标准的无家可归者/边缘居住的PLWHA可以以与居住的PLWHA相似的比率受益于HAART,而且鉴于扩大HAART的使用对个人和社区的好处,迫切需要采取干预措施,以确定艾滋病毒血清阳性的无家可归者/边缘居住的个人,并使他们参与艾滋病毒护理,包括全面支持遵守HAART。
Individuals who are homeless or living in marginal conditions have an elevated burden of infection with HIV. Existing research suggests the HIV/AIDS pandemic in resource-rich settings is increasingly concentrated among members of vulnerable and marginalized populations, including homeless/marginally-housed individuals, who have yet to benefit fully from recent advances in highly-active antiretroviral therapy (HAART). We reviewed the scientific evidence investigating the relationships between inferior housing and the health status, HAART access and adherence and HIV treatment outcomes of people living with HIV/AIDS (PLWHA.) Studies indicate being homeless/marginally-housed is common among PLWHA and associated with poorer levels of HAART access and sub-optimal treatment outcomes. Among homeless/marginally-housed PLWHA, determinants of poorer HAART access/adherence or treatment outcomes include depression, illicit drug use and medication insurance status. Future research should consider possible social- and structural-level determinants of HAART access and HV treatment outcomes that have been shown to increase vulnerability to HIV infection among homeless/marginally-housed individuals. As evidence indicates homeless/marginally-housed PLWHA with adequate levels of adherence can benefit from HAART at similar rates to housed PLWHA, and given the individual and community benefits of expanding HAART use, interventions to identify HIV-seropositive homeless/marginally-housed individuals and engage them in HIV care including comprehensive support for HAART adherence are urgently needed.
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