Challenges and recent progress in drug discovery for tropical diseases.
Challenges and recent progress in drug discovery for tropical diseases.
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DOI:
10.1038/s41586-018-0327-4
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发表时间:
2018-07
期刊:
影响因子:
64.8
通讯作者:
Gilbert IH
中科院分区:
文献类型:
--
作者:
De Rycker M;Baragaña B;Duce SL;Gilbert IH
Infectious tropical diseases have a huge effect in terms of mortality and morbidity, and impose a heavy economic burden on affected countries. These diseases predominantly affect the world’s poorest people. Currently available drugs are inadequate for the majority of these diseases, and there is an urgent need for new treatments. This Review discusses some of the challenges involved in developing new drugs to treat these diseases and highlights recent progress. While there have been notable successes, there is still a long way to go.
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影响因子:
6
作者:
Chatelain E
通讯作者:
Chatelain E
DOI:
10.1073/pnas.1414221111
发表时间:
2014-12-16
影响因子:
11.1
作者:
Belen Jimenez-Diaz, Maria;Ebert, Daniel;Guy, R. Kiplin
通讯作者:
Guy, R. Kiplin
DOI:
10.1056/nejmoa1013911
发表时间:
2011-10-20
期刊:
The New England journal of medicine
影响因子:
--
作者:
Blanc FX;Sok T;Laureillard D;Borand L;Rekacewicz C;Nerrienet E;Madec Y;Marcy O;Chan S;Prak N;Kim C;Lak KK;Hak C;Dim B;Sin CI;Sun S;Guillard B;Sar B;Vong S;Fernandez M;Fox L;Delfraissy JF;Goldfeld AE;CAMELIA (ANRS 1295–CIPRA KH001) Study Team
通讯作者:
CAMELIA (ANRS 1295–CIPRA KH001) Study Team
影响因子:
3.7
作者:
Angulo-Barturen, Inigo;Belen Jimenez-Diaz, Maria;Gargallo-Viola, Domingo
通讯作者:
Gargallo-Viola, Domingo
影响因子:
7.3
作者:
Brown, Dean G.;May-Dracka, Tricia L.;Tommasi, Ruben
通讯作者:
Tommasi, Ruben