Use dose bricks concept to implement nasopharyngeal carcinoma treatment planning.

Use dose bricks concept to implement nasopharyngeal carcinoma treatment planning.
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DOI:
10.1155/2014/720876
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发表时间:
2014
影响因子:
--
通讯作者:
Lee TF
Lee TF
中科院分区:
生物学3区
文献类型:
--
作者:
Wu JM;Yu TJ;Yeh SA;Chao PJ;Huang CJ;Lee TF

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目的。采用“剂量砖”理念实施鼻咽癌治疗方案;此方法尤其适用于钟形鼻咽癌病例。材料和方法。使用五个非共面区域来完成剂量砖技术治疗计划。这五个视野包括(a)右上前斜肌(RSAO)、(b)左上前斜肌(LSAO)、(c)右前斜肌(RAO)、(d)左前斜肌(LAO)和(e)上下顶点(SIV)。在该技术中,使用非发散准直器中心轴平面来创建不同的邻接场边缘,而正常器官则被多叶准直器阻挡。结果。所得的 92% 等剂量曲线涵盖了 CTV,而最大剂量约为 115%。大约 50% 体积的腮腺获得了总剂量的 10-15%,50% 体积的大脑获得了不到总剂量的 20%。脊髓仅接受 5% 的分散剂量。结论。与IMRT相比,计划时间和成本的支出,“剂量砖”毕竟可以作为鼻咽癌适形治疗计划中的可选实施方式被接受;此外,如果可以执行器官保留和非共面技术,该方法也适合其他非头颈部病变的需要。
Purpose. A “dose bricks” concept has been used to implement nasopharyngeal carcinoma treatment plan; this method specializes particularly in the case with bell shape nasopharyngeal carcinoma case. Materials and Methods. Five noncoplanar fields were used to accomplish the dose bricks technique treatment plan. These five fields include (a) right superior anterior oblique (RSAO), (b) left superior anterior oblique (LSAO), (c) right anterior oblique (RAO), (d) left anterior oblique (LAO), and (e) superior inferior vertex (SIV). Nondivergence collimator central axis planes were used to create different abutting field edge while normal organs were blocked by multileaf collimators in this technique. Results. The resulting 92% isodose curves encompassed the CTV, while maximum dose was about 115%. Approximately 50% volume of parotid glands obtained 10–15% of total dose and 50% volume of brain obtained less than 20% of total dose. Spinal cord receives only 5% from the scatter dose. Conclusions. Compared with IMRT, the expenditure of planning time and costing, “dose bricks” may after all be accepted as an optional implementation in nasopharyngeal carcinoma conformal treatment plan; furthermore, this method also fits the need of other nonhead and neck lesions if organ sparing and noncoplanar technique can be executed.
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