Synthesis and characterization of ultra-small superparamagnetic iron oxide nanoparticles thinly coated with silica.

Synthesis and characterization of ultra-small superparamagnetic iron oxide nanoparticles thinly coated with silica.
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DOI:
10.1088/0957-4484/19/33/335601
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发表时间:
2008-08-20
期刊:
影响因子:
3.5
通讯作者:
Dobson PJ
Dobson PJ
中科院分区:
材料科学3区
文献类型:
--
作者:
Bumb A;Brechbiel MW;Choyke PL;Fugger L;Eggeman A;Prabhakaran D;Hutchinson J;Dobson PJ

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Ultra-small superparamagnetic iron oxide nanoparticles (SPIOs) were synthesized by co-precipitation of iron chloride salts with ammonia and then encapsulated with thin (~2nm) layers of silica. The particles have been characterized for size, diffraction pattern, surface charge, and magnetic properties. This rapid and economical synthesis has a number of industrial applications; however, the silica-coated particles have been optimized for use in medical applications as MR contrast agents, biosensors, DNA capturing, bioseparation and enzyme immobilization
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