The rectum, anal sphincter and puborectalis muscle show different contraction wave forms during prolonged measurement with a simulated feces.
The rectum, anal sphincter and puborectalis muscle show different contraction wave forms during prolonged measurement with a simulated feces.
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DOI：
10.1038/s41598-023-50655-7
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发表时间：
2024-01-03
影响因子：
4.6
通讯作者：
中科院分区：
文献类型：
--
作者：
直肠、耻骨直肠肌和肛门括约肌的收缩模式必须被研究以了解排便。6名受试者具有使用Fecobionics研究的收缩波形。采用症状问卷、气囊排出试验、肛门直肠测压等方法进行对照研究。在直肠中填充Fecobionics袋，以达到排便量，并在受试者尝试排空器械前进行4小时测量。用快速傅立叶变换分析了压力和弯曲角（BA）的变化。4名正常人血压和BA出现低频波（< 0.06 Hz）。记录之间的波是不协调的，除了后方和袋的压力。峰值波幅出现在0.02-0.04 Hz。峰值1（p < 0.001）和峰值2振幅（p < 0.005）的压力和BA不同。峰1的前压力振幅大于其他（后和BA，p < 0.05;袋，p < 0.005），峰2的前压力振幅大于袋压力（p < 0.005）和BA（p < 0.05）。1例受试者被认为便秘，与正常受试者相比，前压振幅较低，其他参数振幅增加。第6例受试者反应过度，与其他受试者不同。总之，直肠、肛门括约肌和耻骨直肠肌在长时间测量中显示出不同的收缩波。这些数据需要进行更大规模的研究，以更好地了解正常排便、粪便保留模式以及对肛门直肠疾病的影响。
Contractile patterns in rectum, puborectalis muscle and anal sphincter must be studied to understand defecation. Six subjects had contractile waveforms studied with Fecobionics. Symptom questionnaires, balloon expulsion test and anorectal manometry were done for reference. The Fecobionics bag was filled in rectum to urge-to-defecate volume and measurements were done for 4 h before the subjects attempted to evacuate the device. Pressures and bend angle (BA) variations were analyzed with Fast Fourier Transformation. Four normal subjects exhibited low frequency waves (< 0.06 Hz) for pressures and BA. The waves were uncoordinated between recordings, except for rear and bag pressures. Peak wave amplitudes occurred at 0.02–0.04 Hz. Pressures and the BA differed for peak 1 (p < 0.001) and peak 2 amplitudes (p < 0.005). The front pressure amplitude was bigger than the others (rear and BA, p < 0.05; bag, p < 0.005) for peak 1, and bigger than bag pressure (p < 0.005) and BA (p < 0.05) for peak 2. One subject was considered constipated with lower front pressure amplitudes compared to normal subjects and increased amplitudes for other parameters. The sixth subject was hyperreactive and differed from the other subjects. In conclusion, the rectum, anal sphincter and puborectalis muscle showed different contraction waves during prolonged measurements. The data call for larger studies to better understand normal defecation, feces-withholding patterns, and the implications on anorectal disorders.
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影响因子：
29.4
作者：
通讯作者：
--
影响因子：
3.6
作者：
通讯作者：
--
影响因子：
2.4
作者：
GIBBONS, CP;BANNISTER, JJ;READ, NW
通讯作者：
READ, NW
DOI：
10.1097/00005176-199610000-00007
发表时间：
1996-10-01
影响因子：
2.9
作者：
Benninga, MA;Buller, HA;Taminiau, JAJM
通讯作者：
Taminiau, JAJM
影响因子：
3.3
作者：
Chen, S. -C.;Futaba, K.;Gregersen, H.
通讯作者：
Gregersen, H.