Databases and collaboration require standards for human stem cell research.

Databases and collaboration require standards for human stem cell research.
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DOI:
10.1016/j.drudis.2014.10.006
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发表时间:
2015-03
影响因子:
7.4
通讯作者:
Ekins S
Ekins S
中科院分区:
医学2区
文献类型:
--
作者:
Litterman NK;Ekins S

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如果干细胞研究要实现其预期的潜力,该领域需要增加合作和透明度。这可以通过创建遵循这些标准的标准和数据库来促进。干细胞研究正处于对人类健康具有巨大潜力的重要时刻,一些国家已采取关键举措加快商业化,但在获取和利用过去和目前的研究成果方面存在差距。我们现在提出了一项协调一致的计划,可以采取一种更加合作的方法,并确保所有的研究工作都能在整个社区中得到利用。为学术界和工业界的干细胞组创建一个明确的集中式数据库存储库,或至少是统一的数据存储库,在需要时实现安全的有选择的数据共享,可能提供全球寻求的核心结构并保护知识产权。干细胞实验最小信息的开发可能是关键。
If stem cell research is to achieve its expected potential the field needs an increase in collaboration and transparency. This may be facilitated by the creation of standards and databases that adhere to them. Stem cell research is at an important juncture with significant potential for human health and several countries have key initiatives to expedite commercialization, there are gaps in capturing and exploiting the results of past and current research. We now propose a concerted plan that could be taken to foster a more collaborative approach and ensure that all research efforts can be leveraged across the community. The creation of a definitive centralized database repository, or at least harmonized data repositories, for stem cell groups in academia and industry, enabling secure selective sharing of data when needed, may provide the core structure that is sought globally and protect intellectual property. The development of Minimum Information About Stem Cell Experiments may be key.
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