Preliminary Study on the Clinical Significance and Methods of Using Carbon Nanoparticles in Endoscopic Papillary Thyroid Cancer Surgery.

Preliminary Study on the Clinical Significance and Methods of Using Carbon Nanoparticles in Endoscopic Papillary Thyroid Cancer Surgery.
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DOI:
10.1155/2021/6652315
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发表时间:
2021
影响因子:
--
通讯作者:
Yu J
Yu J
中科院分区:
医学4区
文献类型:
--
作者:
Rao S;Wang Z;Pan C;Wang Y;Lin Z;Pan Z;Yu J

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本研究旨在探讨CN在内镜下治疗PTC的临床意义和方法。 随机入组108例患者,分为两组,其中注射CN组50例,注射CN,对照组58例,不注射CN。对所有病例进行癌肿大小、淋巴结数量、甲状旁腺损伤情况等分析。 所有操作均顺利完成。对照组淋巴结清扫数为274个,CN注射组淋巴结清扫数为322个(黑染率为87%)。 CN注射组平均淋巴结数量为6.44±2.08个,明显高于对照组(4.72±1.89个)。与 CN 注射组相比,对照组偶发甲状旁腺切除术的发生率相对较高(对照组为 27.6%,CN 注射组为 12%,P=0.045)。然而,甲状旁腺功能减退症的发生率未能显示两组之间存在显着差异。 内镜PTC手术中应用CN可提高淋巴结的检出率,并在一定程度上减少甲状旁腺的损伤。
The purpose of this study was to find the clinical significance and methods of using CN in endoscopic treatment for PTC. A total of 108 cases were randomly enrolled and divided into two groups, with 50 cases in the CN injection group who were injected with CN and 58 cases in the control group with no CN injection. All cases were analyzed with the size of carcinoma, the number of lymph node, and parathyroid gland injury. All operations were successfully completed. The lymph node dissection number was 274 for the control group and 322 (the rate of black stained was 87%) for the CN injection group. The average number of lymph nodes in the CN injection group was 6.44 ± 2.08, which was significantly higher than that in the control group (4.72 ± 1.89). The control group had a relatively higher incidence of incidental parathyroidectomy, compared to the CN injection group (27.6% in the control group vs. 12% in the CN injection group, P=0.045). However, the incidence of hypoparathyroidism failed to show the significant difference between the two groups. Using CN in endoscopic PTC surgery could increase the detection rate of lymph nodes and reduce the injury of parathyroid glands to a certain extent.
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