Source reconstruction via the spatiotemporal Kalman filter and LORETA from EEG time series with 32 or fewer electrodes

Source reconstruction via the spatiotemporal Kalman filter and LORETA from EEG time series with 32 or fewer electrodes
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通过时空卡尔曼滤波器和 LORETA 根据 32 个或更少电极的 EEG 时间序列进行源重建

DOI:
10.1109/embc.2017.8037295
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发表时间:
2017
期刊:
2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
影响因子:
--
通讯作者:
M. Siniatchkin
M. Siniatchkin
中科院分区:
--
文献类型:
--
作者:
L. Hamid;A. Al Farawn;I. Merlet;N. Japaridze;U. Heute;U. Stephani;A. Galka;F. Wendling;M. Siniatchkin

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无创脑电图(EEG)的临床常规通常使用8 - 40个电极进行,特别是在长期监测、婴儿或急诊护理中。在临床和科学脑成像中需要开发可以从这些低密度EEG记录重建脑源的逆解方法。在这篇原理证明论文中,我们研究了时空卡尔曼滤波器(STKF)在9-,19-和32-电极EEG源重建中的性能。我们使用了最先进的神经元群体模型从侧额和侧颞脑源产生的癫痫棘波的模拟EEG数据。为了验证源重建,我们将STKF结果与模拟源的位置和低分辨率脑电磁断层扫描(LORETA)标准逆解的结果进行了比较。与LORETA相比,STKF始终显示出更小的定位偏差,尤其是当电极数量减少时。结果鼓励进一步研究STKF在低密度EEG记录的脑活动源重建中的应用。
The clinical routine of non-invasive electroencephalography (EEG) is usually performed with 8–40 electrodes, especially in long-term monitoring, infants or emergency care. There is a need in clinical and scientific brain imaging to develop inverse solution methods that can reconstruct brain sources from these low-density EEG recordings. In this proof-of-principle paper we investigate the performance of the spatiotemporal Kalman filter (STKF) in EEG source reconstruction with 9-, 19- and 32- electrodes. We used simulated EEG data of epileptic spikes generated from lateral frontal and lateral temporal brain sources using state-of-the-art neuronal population models. For validation of source reconstruction, we compared STKF results to the location of the simulated source and to the results of low-resolution brain electromagnetic tomography (LORETA) standard inverse solution. STKF consistently showed less localization bias compared to LORETA, especially when the number of electrodes was decreased. The results encourage further research into the application of the STKF in source reconstruction of brain activity from low-density EEG recordings.
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