Diverse Epidemiology of Leptospira serovars Notified in New Zealand, 1999-2017.
Diverse Epidemiology of Leptospira serovars Notified in New Zealand, 1999-2017.
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DOI：
10.3390/pathogens9100841
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发表时间：
2020-10-14
期刊：
影响因子：
--
通讯作者：
Benschop J
中科院分区：
文献类型：
--
作者：
Nisa S;Wilkinson DA;Angelin-Bonnet O;Paine S;Cullen K;Wight J;Baker MG;Benschop J
新西兰的钩端螺旋体病与动物接触职业以及Hardjo和Pomona血清型密切相关。然而，最近的数据表明这些模式发生了变化，因此对1999年至2017年钩端螺旋体病的血清特异性流行病学进行了调查。19年平均年发病率为2.01/10万。早期（1999-2007）和晚期（2008-2017）研究期比较显示，所有病例中balum血清型（IRR: 1.59, 95% CI: 1.22-2.09）和Tarassovi血清型（IRR: 1.75, 95% CI: 1.13-2.78）的报告率显著增加，所有病例中Hardjo和Pomona血清型的报告率均有所下降。Ballum发病高峰在冬季，Hardjo发病高峰在春季，Tarassovi发病高峰在夏季。发病率最高的是Māori（2.24/10万），以Hardjo和Pomona为主。按职业分层，肉制品工人的Hardjo患病率最高（57.29/10万），Pomona患病率最高（45.32/10万），农民的Ballum患病率最高（11.09/10万），奶牛场的Tarassovi患病率最高（12.59/10万）。空间分析显示，Hawke 's Bay的Hardjo和Pomona占优势，西海岸和Northland的Ballum占优势，Waikato、Taranaki和Northland的Tarassovi占优势。这项研究强调了新西兰人钩端螺旋体病的血清特异性异质性，在制定控制和预防策略时应考虑到这一点。
Leptospirosis in New Zealand has been strongly associated with animal-contact occupations and with serovars Hardjo and Pomona. However, recent data suggest changes in these patterns, hence, serovar-specific epidemiology of leptospirosis from 1999 to 2017 was investigated. The 19-year average annual incidence is 2.01/100,000. Early (1999–2007) and late (2008–2017) study period comparisons showed a significant increase in notifications with serovar Ballum (IRR: 1.59, 95% CI: 1.22–2.09) in all cases and serovar Tarassovi (IRR: 1.75, 95% CI: 1.13–2.78) in Europeans and a decrease in notifications with serovars Hardjo and Pomona in all cases. Incidences of Ballum peaked in winter, Hardjo peaked in spring and Tarassovi peaked in summer. Incidence was highest in Māori (2.24/100,000) with dominant serovars being Hardjo and Pomona. Stratification by occupation showed meat workers had the highest incidence of Hardjo (57.29/100,000) and Pomona (45.32/100,000), farmers had the highest incidence of Ballum (11.09/100,000) and dairy farmers had the highest incidence of Tarassovi (12.59/100,000). Spatial analysis showed predominance of Hardjo and Pomona in Hawke’s Bay, Ballum in West Coast and Northland and Tarassovi in Waikato, Taranaki and Northland. This study highlights the serovar-specific heterogeneity of human leptospirosis in New Zealand that should be considered when developing control and prevention strategies.
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影响因子：
3.7
作者：
Goris MG;Kikken V;Straetemans M;Alba S;Goeijenbier M;van Gorp EC;Boer KR;Wagenaar JF;Hartskeerl RA
通讯作者：
Hartskeerl RA
DOI：
10.1007/s10096-012-1551-8
发表时间：
2012-09-01
影响因子：
4.5
作者：
Bakoss, P.;Machacova, E.;Jarekova, J.
通讯作者：
Jarekova, J.
影响因子：
8.4
作者：
Baranton, G;Postic, D
通讯作者：
Postic, D
DOI：
10.1080/09603120601124181
发表时间：
2007-02-01
影响因子：
3.2
作者：
Firth, Hilda M.;Rothstein, Diana S.;McBride, David I.
通讯作者：
McBride, David I.
影响因子：
--
作者：
Haake, David A.;Levett, Paul N.
通讯作者：
Levett, Paul N.