Quantitative trait loci for lifespan of mated Drosophila melanogaster affect both sexes.
Quantitative trait loci for lifespan of mated Drosophila melanogaster affect both sexes.
复制标题
交配果蝇寿命的数量性状基因座影响两性。
DOI:
10.1017/s0016672302005943
复制
发表时间:
2002
期刊:
影响因子:
--
通讯作者:
Nuzhdin,SergeyV
中科院分区:
文献类型:
--
作者:
Reiwitch,SarahG;Nuzhdin,SergeyV
The properties of alleles at quantitative trait loci (QTLs) contributing to variation in lifespan should be described to determine the mechanisms of evolution of life length and to predict its future changes. Previously, we and others conducted genome-wide screens for QTLs that segregate among one panel of recombinant inbred lines (RILs) using a dense molecular marker map. In non-stressful conditions, QTLs effecting the lifespans of virgin females and males were frequently sex specific. In an unrelated panel of RILs, the effects of QTLs in flies maintained in cages with mixed sexes were similar in both sexes. Here, we re-measured the lifespans of the former panel of RILs in cages with mixed sex cohorts. Lifespan declined owing to mating. The amount of decline correlated between sexes within lines. QTLs mapping to the intervals 15A–19C, 50B–57C, 63A–65A, and 96F–99B had similar effects on the lifespans of both males and females. These QTLs have previously been detected in virgin flies surveys and had sex- and/or environment-specific effects.
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DOI:
10.1001/jama.1985.03350440053030
发表时间:
1985
期刊:
JAMA
影响因子:
--
作者:
P. Remington;M. Forman;E. Gentry;J. Marks;G. Hogelin;F. Trowbridge
通讯作者:
F. Trowbridge
影响因子:
6.7
作者:
Gust,SW;Pickens,RW
通讯作者:
Pickens,RW
DOI:
--
发表时间:
1985
期刊:
Journal of the American Medical Association (JAMA)
影响因子:
--
作者:
C. Hennekens;J. Buring
通讯作者:
J. Buring
影响因子:
158.5
作者:
KAUFMAN, DW;HELMRICH, SP;SHAPIRO, S
通讯作者:
SHAPIRO, S
影响因子:
158.5
作者:
ROSENBERG, L;KAUFMAN, DW;SHAPIRO, S
通讯作者:
SHAPIRO, S