Understanding and acting on the developmental origins of health and disease in Africa would improve health across generations.

Understanding and acting on the developmental origins of health and disease in Africa would improve health across generations.
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DOI:
10.1080/16549716.2017.1334985
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发表时间:
2017
影响因子:
2.6
通讯作者:
van Schalkwyk C
van Schalkwyk C
中科院分区:
医学3区
文献类型:
--
作者:
Norris SA;Daar A;Balasubramanian D;Byass P;Kimani-Murage E;Macnab A;Pauw C;Singhal A;Yajnik C;Akazili J;Levitt N;Maatoug J;Mkhwanazi N;Moore SE;Nyirenda M;Pulliam JRC;Rochat T;Said-Mohamed R;Seedat S;Sobngwi E;Tomlinson M;Toska E;van Schalkwyk C

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来自许多高收入和低收入或中等收入国家的数据将关键发育期(特别是怀孕和婴儿期)的暴露与以后的健康和疾病联系起来。非洲面临着持续存在的传染病和新兴的非传染性疾病的巨大挑战,本文开启了辩论的价值,加强发展的健康和疾病的起源(DOHaD)的研究重点在非洲,以应对整个生命过程中的关键公共卫生挑战。我们认为,在非洲应用DOHaD科学来推进生命周期预防计划可以帮助实现可持续发展目标,并有助于改善几代人的健康状况。为了增加DOHaD研究及其在非洲的应用,我们需要动员多部门合作伙伴,利用非洲大陆现有的数据和专业知识,并培养新一代专注于DOHaD的非洲年轻科学家。
Data from many high- and low- or middle-income countries have linked exposures during key developmental periods (in particular pregnancy and infancy) to later health and disease. Africa faces substantial challenges with persisting infectious disease and now burgeoning non-communicable disease.This paper opens the debate to the value of strengthening the developmental origins of health and disease (DOHaD) research focus in Africa to tackle critical public health challenges across the life-course. We argue that the application of DOHaD science in Africa to advance life-course prevention programmes can aid the achievement of the Sustainable Development Goals, and assist in improving health across generations. To increase DOHaD research and its application in Africa, we need to mobilise multisectoral partners, utilise existing data and expertise on the continent, and foster a new generation of young African scientists engrossed in DOHaD.
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