Preferences for oral-fluid-based or blood-based HIV self-testing and provider-delivered testing: an observational study among different populations in Zimbabwe.
Preferences for oral-fluid-based or blood-based HIV self-testing and provider-delivered testing: an observational study among different populations in Zimbabwe.
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DOI：
10.1186/s12879-023-08624-y
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发表时间：
2023-10-17
影响因子：
3.7
通讯作者：
Sibanda, Euphemia L.
中科院分区：
文献类型：
--
作者：
Mavhu, Webster;Makamba, Memory;Hatzold, Karin;Maringwa, Galven;Takaruza, Albert;Mutseta, Miriam;Ncube, Getrude;Cowan, Frances M.;Sibanda, Euphemia L.
关于客户对不同艾滋病毒自我检测(HIVST)和提供者提供的检测选项的偏好以及相关因素的数据有限。我们在不同人群中调查了客户对口服液自检(OFBST)、血液自检(BBST)和提供者提供的血液自检(PDBBT)的偏好。在为普通人群提供艾滋病毒检测服务的诊所(1家城市诊所，1家农村诊所)、寻求自愿医疗男性包皮环切术的男性(VMMC，1家诊所)和女性性工作者(FSW，1家诊所)，客户可以选择使用OFBST、BBST或PDBBT进行检测。一份测试前问卷收集了有关人口统计学和测试历史的信息。在收集了一套完整的自测试剂盒两周后，参与者回答了一份问卷。我们使用Logistic回归来确定选择的预测因素。我们还进行了20次深度访谈，以将量化结果与背景联系起来。2019年5月至6月，我们招募了1244名参与者，其中249人(20%)、251人(20%)、244人(20%)和500人(40%)分别在城市综合诊所、农村诊所、VMMC诊所和FSW诊所就诊。半数(n = 619例，占50.00%)选择全腹膜后支架术，440例(占35%)和185例(占15.0%)分别选择根治性支气管镜和腹腔镜术。在多变量分析中比较选择HIVST的人(OFBST和BBST合并)与不选择HIVST的人，从未结婚的人选择HIVST的可能性较低，从未结婚的人选择HIVST的可能性为0.57(95%CI为0.34~0.93)，已婚的人选择HIVST的可能性为AOR0.56(0.34~0.93)。HIVST偏好随着受教育程度的增加而增加，普通教育、高等教育和大专教育的AOR分别为2.00(1.28-3.13)、2.55(1.28-5.07)、2.76(1.48-5.14)。HIVST偏好随着年龄的增加而降低，AOR为0.97(0.96~0.99)。城市比农村更倾向于选择HIVST，FSW、城市普通和VMMC客户的AOR分别为9.77(5.47-17.41)、3.38(2.03-5.62)和2.23(1.38-3.61)。比较那些选择OFBST和那些选择BBST的人，文化程度较低的参与者选择口腔液体测试的可能性较小，AOR为0.29(0.09-0.92)。大多数测试客户端选择了OFBST，其次是BBST，最后是PDBBT。那些自我评估为不太健康的人更有可能选择PDBBT，这可能促进了联系。结果表明，继续提供所有战略以满足不同人群的需求的重要性，并可能有助于为HIVST试剂盒库存预测和HIVST项目的定制提供信息，以满足不同人群的需求。
There is limited data on client preferences for different HIV self-testing (HIVST) and provider-delivered testing options and associated factors. We explored client preferences for oral-fluid-based self-testing (OFBST), blood-based self-testing (BBST) and provider-delivered blood-based testing (PDBBT) among different populations. At clinics providing HIV testing services to general populations (1 urban, 1 rural clinic), men seeking voluntary medical male circumcision (VMMC, 1 clinic), and female sex workers (FSW, 1 clinic), clients had the option to test using OFBST, BBST or PDBBT. A pre-test questionnaire collected information on demographics and testing history. Two weeks after collecting a self-test kit, participants responded to a questionnaire. We used logistic regression to determine predictors of choices. We also conducted 20 in-depth interviews to contextualise quantitative findings. May to June 2019, we recruited 1244 participants of whom 249 (20%), 251 (20%), 244 (20%) and 500 (40%) were attending urban general, rural, VMMC and FSW clinics, respectively. Half (n = 619, 50%) chose OFBST, 440 (35%) and 185 (15%) chose BBST and PDBBT, respectively. In multivariable analysis comparing those choosing HIVST (OFBST and BBST combined) versus not, those who had never married aOR 0.57 (95% CI 0.34–0.93) and those previously married aOR0.56 (0.34–0.93) were less likely versus married participants to choose HIVST. HIVST preference increased with education, aOR 2.00 (1.28–3.13), 2.55 (1.28–5.07), 2.76 (1.48–5.14) for ordinary, advanced and tertiary education, respectively versus none/primary education. HIVST preference decreased with age aOR 0.97 (0.96–0.99). Urban participants were more likely than rural ones to choose HIVST, aOR 9.77 (5.47–17.41), 3.38 (2.03–5.62) and 2.23 (1.38–3.61) for FSW, urban general and VMMC clients, respectively. Comparing those choosing OFBST with those choosing BBST, less literate participants were less likely to choose oral fluid tests, aOR 0.29 (0.09–0.92). Most testing clients opted for OFBST, followed by BBST and lastly, PDBBT. Those who self-assessed as less healthy were more likely to opt for PDBBT which likely facilitated linkage. Results show importance of continued provision of all strategies in order to meet needs of different populations, and may be useful to inform both HIVST kit stock projections and tailoring of HIVST programs to meet the needs of different populations.
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影响因子：
6
作者：
Perriat D;Balzer L;Hayes R;Lockman S;Walsh F;Ayles H;Floyd S;Havlir D;Kamya M;Lebelonyane R;Mills LA;Okello V;Petersen M;Pillay D;Sabapathy K;Wirth K;Orne-Gliemann J;Dabis F;Universal Test and Treat Trials Consortium (UT3C)
通讯作者：
Universal Test and Treat Trials Consortium (UT3C)
影响因子：
4.4
作者：
Kurth AE;Cleland CM;Chhun N;Sidle JE;Were E;Naanyu V;Emonyi W;Macharia SM;Sang E;Siika AM
通讯作者：
Siika AM
影响因子：
6
作者：
Cambiano, Valentina;Johnson, Cheryl C.;Phillips, Andrew
通讯作者：
Phillips, Andrew
检查使用艾滋病毒自我测试来支持准备准备的使用：系统文献综述。
影响因子：
4.6
作者：
通讯作者：
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影响因子：
4.5
作者：
Mtetwa S;Busza J;Chidiya S;Mungofa S;Cowan F
通讯作者：
Cowan F