Maternal ADHD and Perinatal Prescription Stimulant Use
Maternal ADHD and Perinatal Prescription Stimulant Use
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母亲多动症和围产期处方兴奋剂的使用
DOI：
10.1177/10870547211073472
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发表时间：
2022
影响因子：
3
通讯作者：
J. Farley
中科院分区：
文献类型：
--
作者：
M. Murugappan;Sarah M Westberg;S. Contag;Tanya Melnik;Arun Kumar;A. Rajpurohit;Katie R. Thorsness;J. Farley
目的：描述围产期处方兴奋剂使用的模式和预测因素。研究方法：我们使用MarketScan®商业索赔数据（2013-2018）和重复的横断面研究设计来评估围产期处方兴奋剂的使用。在妊娠不同阶段继续与停止兴奋剂治疗的妇女队列中比较临床/人口统计学特征。使用卡方检验（分类变量）和独立t检验（连续变量）检验相关性的显著性。结果：在612，001例妊娠中，15，413例涉及孕前兴奋剂使用。其中，6，416人（42%）在怀孕前停止了兴奋剂治疗，5，977人（39%）在第一个三月期间停止了兴奋剂治疗，3，020人（19%）继续到后三个三月。与怀孕前停止服用兴奋剂的孕妇相比，那些继续怀孕的孕妇年龄更大（29.9岁对28.9岁），患有更严重的ADHD（3.1对1.8 ADHD相关的账单索赔）。结论：有相当大的异质性在管理ADHD在怀孕期间。
Objective: To describe patterns and predictors of perinatal prescription stimulant use. Methods: We used MarketScan® commercial claims data (2013–2018) and a repeated cross-sectional study design to assess perinatal use of prescription stimulants. Clinical/demographic characteristics were compared across cohorts of women who continued versus discontinued stimulant treatment at various stages of pregnancy. Associations were tested for significance using chi-square tests (categorical variables) and independent t-tests (continuous variables). Results: Out of 612,001 pregnancies, 15,413 involved pre-pregnancy stimulant use. Of these, stimulant treatment was discontinued prior to conception in 6,416 (42%), discontinued during trimester 1 in 5,977 (39%), and continued into later trimesters in 3,020 (19%). Compared with pregnancies involving stimulant discontinuation prior to conception, those that continued into pregnancy occurred in women who were older (29.9 vs. 28.9 years) and had more severe ADHD (3.1 vs. 1.8 ADHD-related billing claims). Conclusions: There is considerable heterogeneity in the management of ADHD during pregnancy.
影响因子：
0.9
作者：
Muhammed Ather;G. Salmon
通讯作者：
Muhammed Ather;G. Salmon
影响因子：
7.2
作者：
Cohen JM;Hernández-Díaz S;Bateman BT;Park Y;Desai RJ;Gray KJ;Patorno E;Mogun H;Huybrechts KF
通讯作者：
Huybrechts KF
影响因子：
17.7
作者：
Kessler, RC;Adler, L;Zaslavsky, AM
通讯作者：
Zaslavsky, AM