Impact of different coils on biochemical T2 and T2* relaxation time mapping of articular patella cartilage
Impact of different coils on biochemical T2 and T2* relaxation time mapping of articular patella cartilage
复制标题
不同线圈对髌骨软骨生化T2和T2*弛豫时间图的影响
DOI：
10.1007/s00256-013-1699-z
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发表时间：
2013
影响因子：
2.1
通讯作者：
Welsch GH
中科院分区：
文献类型：
--
作者：
Pachowsky ML;Trattnig S;Apprich S;Mauerer A;Zbyn S;Welsch GH
我们的研究的目的是评估T2和T2* 弛豫时间值在健康志愿者使用三种不同的线圈在3.0特斯拉MRI和他们的影响的定量values.Methods15志愿者进行了检查，在同一个3特斯拉MR单位使用三种不同的线圈：（i）专用的八通道膝关节相控阵线圈;（ii）八通道多用途线圈，和（iii）单通道1H表面线圈。T2和T2* 弛豫时间测量分别由多回波自旋回波制备 梯度回波序列对髌骨软骨进行半自动感兴趣区域分析。为了分层，进行了次区域分析（深-浅软骨层）。统计方差分析performed.ResultsThe平均定量T2值显示在所有比较组合的统计学显着差异。平均定量T2* 值之间的差异略低于T2评价，只有（i）和（ii）之间的比较显示出显著差异。T2和T2* 值的结果显示，与所使用的线圈无关，与深部区域相比，浅表区域中的值更高（p< 0.05）。观察信号变化，所有线圈在深层中显示出明显更高的值（因此更多的信号变化作为噪声的标志）。的可靠性的验证表明，一个高的类内相关系数，因此一个非常高的可扩展性（ICC为0.870和0.905之间的T2映射和0.879和0.888之间的T2 * mapping）。
ObjectiveThe purpose of our study was to assess T2 and T2* relaxation time values of patella cartilage in healthy volunteers using three different coils at 3.0 Tesla MRI and their influence on the quantitative values.MethodsFifteen volunteers were examined on the same 3-Tesla MR unit using three different coils: (i) a dedicated eight-channel knee phased-array coil; (ii) an eight-channel multi-purpose coil, and (iii) a one-channel 1H surface coil. T2 and T2* relaxation time measurements were prepared by a multi-echo spinecho respectively a gradient-echo sequence. A semi-automatic region-of-interest analysis was performed for patella cartilage. To allow stratification, a subregional analysis was carried out (deep-superficial cartilage layer). Statistical analysis-of-variance was performed.ResultsThe mean quantitative T2 values showed statistically significant differences in all comparison combinations. The differences between the mean quantitative T2* values were slightly less pronounced than the T2 evaluation and only the comparison between (i) and (ii) showed a significant difference. The results of T2 and T2* values showed, independent of the used coil, higher values in the superficial zone compared to the deep zone (p< 0.05). Looking at the signal alterations, all coils showed clearly higher values (and thus more signal alterations as a sign of noise) in the deep layer. The validation of the reliability showed a high intra-class correlation coefficient and hence a very high plausibility (ICC was between 0.870 and 0.905 for T2 mapping and between 0.879 and 0.888 for T2* mapping).ConclusionsThe present results demonstrate that biochemical T2 and T2* mapping is significantly dependent on the utilized coil.
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DOI：
10.1097/00003086-200110001-00034
发表时间：
2001-10-01
影响因子：
4.2
作者：
Chung, CB;Frank, LR;Resnick, D
通讯作者：
Resnick, D
影响因子：
4.4
作者：
Dietrich, Olaf;Raya, Jose G.;Schoenberg, Stefan O.
通讯作者：
Schoenberg, Stefan O.
影响因子：
--
作者：
Raynauld, JP;Martel-Pelletier, J;Pelletier, JP
通讯作者：
Pelletier, JP
通过质子磁共振显微镜研究工程软骨组织对生化制剂的反应。
影响因子：
--
作者：
Potter,K;Butler,JJ;Horton,WE;Spencer,RG
通讯作者：
Spencer,RG