Interictal ripples nested in epileptiform discharge help to identify the epileptogenic zone in neocortical epilepsy
Interictal ripples nested in epileptiform discharge help to identify the epileptogenic zone in neocortical epilepsy
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癫痫样放电中嵌套的发作间期波纹有助于识别新皮质癫痫的致痫区
DOI：
10.1016/j.clinph.2017.03.033
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发表时间：
2017-06
影响因子：
4.7
通讯作者：
Najm Imad M.
中科院分区：
文献类型：
--
作者：
Wang Shuang;So Norman K.;Jin Bo;Wang Irene Z.;Bulacio Juan C.;Enatsu Rei;Dai Shenyi;Chen Zhong;Gonzalez-Martinez Jorge;Najm Imad M.
本研究旨在确定发作间期波纹的亚型，有助于划定癫痫发生区在neocortical epilepsy. MethodsTotal 25例局灶性neocortical epilepsy谁进行了侵入性脑电图（EEG）评估和随后的手术。随访至少2年。在慢波睡眠期间识别出发作间期波纹（80-250 Hz）和快速波纹（250-500 Hz）。新皮层波纹被定义为I型波纹时，他们叠加在癫痫样放电，和II型波纹时，他们独立发生。切除率进行计算，以呈现在何种程度上显示发作间期事件或癫痫发作区（SOZ）的皮质区被完全removed.ResultsFast波纹和I型和II型波纹被发现在8，19，和21例，分别。只有发作间期快波或I型波切除率较高与Engel 1a手术结局相关。结论I型波可辅助定位新皮质癫痫的致痫灶。
ObjectiveThis study aimed to identify the subtype of interictal ripples that help delineate the epileptogenic zone in neocortical epilepsy.MethodsTotally 25 patients with focal neocortical epilepsy who had invasive electroencephalography (EEG) evaluation and subsequent surgery were included. They were followed up for at least 2 years. Interictal ripples (80–250 Hz) and fast ripples (250–500 Hz) during slow-wave sleep were identified. Neocortical ripples were defined as type I ripples when they were superimposed on epileptiform discharges, and as type II ripples when they occurred independently. Resection ratio was calculated to present the extent to which the cortical area showing an interictal event or the seizure onset zone (SOZ) was completely removed.ResultsFast ripples and types I and II ripples were found in 8, 19, and 21 patients, respectively. Only the higher resection ratio of interictal fast or type I ripples was correlated to the Engel 1a surgical outcome.ConclusionsType I ripples could assist in localizing the epileptogenic zone in neocortical epilepsy.SignificanceType I and fast ripples both may be pathological high-frequency oscillations.
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影响因子：
4.8
作者：
See, Siew-Ju;Jehi, Lara E.;Bingaman, William
通讯作者：
Bingaman, William
影响因子：
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通讯作者：
Trinka E
影响因子：
4.8
作者：
Nagasawa, Tetsuro;Juhasz, Csaba;Rothermel, Robert;Hoechstetter, Karsten;Sood, Sandeep;Asano, Eishi
通讯作者：
Asano, Eishi