Urinary incontinence in women.
Urinary incontinence in women.
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DOI：
10.1038/nrdp.2017.42
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发表时间：
2017-07-06
期刊：
影响因子：
--
通讯作者：
Cartwright R
中科院分区：
文献类型：
--
作者：
Aoki Y;Brown HW;Brubaker L;Cornu JN;Daly JO;Cartwright R
尿失禁症状在妇女中非常普遍，对与健康有关的生活质量有重大影响，并与相当大的个人和社会支出有关。描述了两种主要类型：压力性尿失禁，与体力消耗相关的尿漏；以及紧迫性尿失禁，与突如其来的强迫排尿欲望有关。出现这两种症状的女性被认为患有混合性尿失禁。研究揭示了尿失禁的潜在原因重叠，包括逼尿肌或盆底肌肉的功能障碍，储存和排尿的神经控制功能障碍，以及膀胱内局部环境的扰动。对尿失禁的全面诊断评估需要病史、体检、尿检、生活质量评估，如果最初的治疗失败，还需要侵入性尿动力学检查。干预措施可以包括非手术选择(如改变生活方式、盆底肌肉训练和药物)和手术选择，以支持尿路或增加膀胱容量。未来的研究方向可能越来越多地以通过了解大小便失禁的环境和遗传风险来进行初级预防为目标。
Urinary incontinence symptoms are highly prevalent among women, have a substantial effect on health-related quality of life and are associated with considerable personal and societal expenditure. Two main types are described: stress urinary incontinence, in which urine leaks in association with physical exertion, and urgency urinary incontinence, in which urine leaks in association with a sudden compelling desire to void. Women who experience both symptoms are considered as having mixed urinary incontinence. Research has revealed overlapping potential causes of incontinence, including dysfunction of the detrusor muscle or muscles of the pelvic floor, dysfunction of the neural controls of storage and voiding, and perturbation of the local environment within the bladder. A full diagnostic evaluation of urinary incontinence requires a medical history, physical examination, urinalysis, assessment of quality of life and, when initial treatments fail, invasive urodynamics. Interventions can include non-surgical options (such as lifestyle modifications, pelvic floor muscle training and drugs) and surgical options to support the urethra or increase bladder capacity. Future directions in research may increasingly target primary prevention through understanding of environmental and genetic risks for incontinence.
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影响因子：
2.1
作者：
Abraham, L;Hareendran, A;Noble, JG
通讯作者：
Noble, JG
DOI：
10.1196/annals.1389.034
发表时间：
2007-01-01
期刊：
REPRODUCTIVE BIOMECHANICS
影响因子：
--
作者：
Ashton-Miller, James A.;Delancey, John O. L.
通讯作者：
Delancey, John O. L.
影响因子：
2.6
作者：
Botlero, Roslin;Urquhart, Donna M.;Bell, Robin J.
通讯作者：
Bell, Robin J.
影响因子：
2
作者：
Beyar, Netta;Groutz, Asnat
通讯作者：
Groutz, Asnat
防止尿路感染：朝着有效的大肠杆菌疫苗迈进。
影响因子：
6.2
作者：
Brumbaugh AR;Mobley HL
通讯作者：
Mobley HL