The Involvement of Mg(2+) in Regulation of Cellular and Mitochondrial Functions.
The Involvement of Mg(2+) in Regulation of Cellular and Mitochondrial Functions.
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DOI:
10.1155/2017/6797460
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发表时间:
2017
影响因子:
--
通讯作者:
Racay P
中科院分区:
文献类型:
--
作者:
Pilchova I;Klacanova K;Tatarkova Z;Kaplan P;Racay P
Mg2+ is an essential mineral with pleotropic impacts on cellular physiology and functions. It acts as a cofactor of several important enzymes, as a regulator of ion channels such as voltage-dependent Ca2+ channels and K+ channels and on Ca2+-binding proteins. In general, Mg2+ is considered as the main intracellular antagonist of Ca2+, which is an essential secondary messenger initiating or regulating a great number of cellular functions. This review examines the effects of Mg2+ on mitochondrial functions with a particular focus on energy metabolism, mitochondrial Ca2+ handling, and apoptosis.
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影响因子:
3
作者:
Corona, Juan Carlos;Duchen, Michael R.
通讯作者:
Duchen, Michael R.
DOI:
10.1038/nrcardio.2016.203
发表时间:
2017-04
期刊:
Nature reviews. Cardiology
影响因子:
--
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Brown DA;Perry JB;Allen ME;Sabbah HN;Stauffer BL;Shaikh SR;Cleland JG;Colucci WS;Butler J;Voors AA;Anker SD;Pitt B;Pieske B;Filippatos G;Greene SJ;Gheorghiade M
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Gheorghiade M
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4.6
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de Baaij JH;Arjona FJ;van den Brand M;Lavrijsen M;Lameris AL;Bindels RJ;Hoenderop JG
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Hoenderop JG
影响因子:
3.5
作者:
FAVARON, M;BERNARDI, P
通讯作者:
BERNARDI, P
影响因子:
3
作者:
Boelens, Age D.;Pradhan, Ranjan K.;Blomeyer, Christoph A.;Camara, Amadou K. S.;Dash, Ranjan K.;Stowe, David F.
通讯作者:
Stowe, David F.