Escherichia coli strains belonging to phylogenetic group B2 have superior capacity to persist in the intestinal microflora of infants.
Escherichia coli strains belonging to phylogenetic group B2 have superior capacity to persist in the intestinal microflora of infants.
复制标题
属于系统发育群 B2 的大肠杆菌菌株在婴儿肠道菌群中具有卓越的持久能力。
DOI：
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发表时间：
2005
影响因子：
6.4
通讯作者：
I. Adlerberth
中科院分区：
文献类型：
--
作者：
F. Nowrouzian;A. Wold;I. Adlerberth
Escherichia coli strains segregate into 4 phylogenetic groups, designated "A," "B1," "B2," and "D." Pathogenic strains belong to group B2 and, to a lesser extent, group D, which more frequently carry virulence-factor genes than do group A strains and group B1 strains. This study investigated whether the capacity of E. coli to persist in the human intestine is related to its phylogenetic type. Resident (n=58) and transient (n=19) commensal E. coli strains isolated during a longitudinal study of 70 Swedish infants and previously tested for virulence-factor-gene carriage were tested for phylogenetic type. Of the strains resident in the intestinal microflora, 60% belonged to group B2, compared with only 21% of the transient strains (P=.004). In logistic regression, group B2 type predicted persistence in the intestinal microflora, independent of carriage of all investigated virulence-factor genes, including genes for P fimbriae (P=.03). Thus, group B2 strains appear to possess yet unidentified traits that enhance their survival in the human intestine.
影响因子：
6.4
作者：
Johnson, JR;Stell, AL
通讯作者：
Stell, AL
影响因子：
6.4
作者：
Johnson, JR;Delavari, P;Stell, AL
通讯作者：
Stell, AL