Cellular compartmentation follows rules: The Schnepf theorem, its consequences and exceptions

Cellular compartmentation follows rules: The Schnepf theorem, its consequences and exceptions
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细胞划分遵循规则:施奈普夫定理、其结果和例外

DOI:
10.1002/bies.201700030
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发表时间:
2017
期刊:
影响因子:
4
通讯作者:
Maier UG
Maier UG
中科院分区:
生物学3区
文献类型:
--
作者:
Moog D;Maier UG

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细胞内膜和隔室的空间组织是否受制于任何规则?细胞区隔作用在原核生物和真核生物中是不同的,因为它只在真核生物中高度存在。1964年,Eberhard Schnepf教授提出了分隔规则(Schnepf定理),认为生物膜是负责细胞分隔的主要物理结构,通常将质相和非质相分开。在这里,我们回顾并重新研究Schnepf定理,将该定理应用于不同的细胞结构,从细菌细胞到具有细胞器和隔间的真核生物。总而言之,我们可以确认Schnepf定理的一般正确性,并指出只有在特殊情况下才有明确的例外情况,如内共生和寄生。
Is the spatial organization of membranes and compartments within cells subjected to any rules? Cellular compartmentation differs between prokaryotic and eukaryotic life, because it is present to a high degree only in eukaryotes. In 1964, Prof. Eberhard Schnepf formulated the compartmentation rule (Schnepf theorem), which posits that a biological membrane, the main physical structure responsible for cellular compartmentation, usually separates a plasmatic form a non‐plasmatic phase. Here we review and re‐investigate the Schnepf theorem by applying the theorem to different cellular structures, from bacterial cells to eukaryotes with their organelles and compartments. In conclusion, we can confirm the general correctness of the Schnepf theorem, noting explicit exceptions only in special cases such as endosymbiosis and parasitism.
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发表时间: 2009-05
期刊: Biochimica et biophysica acta
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