Measures to Evaluate the Effects of DBS on Speech Production.
Measures to Evaluate the Effects of DBS on Speech Production.
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DOI：
10.1016/j.jneuroling.2011.08.006
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发表时间：
2012-03
影响因子：
2
通讯作者：
Bunton, Kate
中科院分区：
文献类型：
--
作者：
Weismer, Gary;Yunusova, Yana;Bunton, Kate
本文的目的是回顾和评估言语产生的措施，可用于记录脑深部电刺激（DBS）对言语性能的影响，特别是在帕金森病（PD）患者中。首先介绍了这些措施的一个小的评价标准，然后考虑几个语音生理学和语音声学措施，已被研究频繁，并在文献中报道正常的语音生产，语音生产受神经运动障碍（构音障碍）。根据评价标准对每项措施进行审查和评价。嵌入在这个审查和评估是一个新的数据相关的语音运动的语音清晰度措施，在扬声器与PD，肌萎缩侧索硬化症（ALS），和控制扬声器（CS）的介绍。这些数据被用来支持的结论，即在目前的第二共振峰转换（F2斜率），声学措施的斜率，是非常适合于作出推断的语音运动和预测语音清晰度。不应排除使用其他措施，但是，我们鼓励进一步发展的评价标准，旨在探讨DBS或任何治疗的影响，言语生产和沟通技能的潜在影响的言语措施。
The purpose of this paper is to review and evaluate measures of speech production that could be used to document effects of Deep Brain Stimulation (DBS) on speech performance, especially in persons with Parkinson disease (PD). A small set of evaluative criteria for these measures is presented first, followed by consideration of several speech physiology and speech acoustic measures that have been studied frequently and reported on in the literature on normal speech production, and speech production affected by neuromotor disorders (dysarthria). Each measure is reviewed and evaluated against the evaluative criteria. Embedded within this review and evaluation is a presentation of new data relating speech motions to speech intelligibility measures in speakers with PD, amyotrophic lateral sclerosis (ALS), and control speakers (CS). These data are used to support the conclusion that at the present time the slope of second formant transitions (F2 slope), an acoustic measure, is well suited to make inferences to speech motion and to predict speech intelligibility. The use of other measures should not be ruled out, however, and we encourage further development of evaluative criteria for speech measures designed to probe the effects of DBS or any treatment with potential effects on speech production and communication skills.
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