Central Circadian Clock Regulates Energy Metabolism.
Central Circadian Clock Regulates Energy Metabolism.
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DOI:
10.1007/978-981-13-1286-1_5
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发表时间:
2018
影响因子:
--
通讯作者:
Sun Z
中科院分区:
文献类型:
--
作者:
Ding G;Gong Y;Eckel-Mahan KL;Sun Z
Our body not only responds to environmental changes but also anticipates them. The light and dark cycle with the period of about 24 hours is a recurring environmental change that determines the diurnal variation in food availability and safety from predators in nature. As a result, the circadian clock is evolved in most animals to align locomotor behaviors and energy metabolism with the light cue. The central circadian clock in mammals is located at the suprachiasmatic nucleus (SCN) of the hypothalamus in the brain. We here review the molecular and anatomic architecture of the central circadian clock in mammals; describe the experimental and observational evidence that suggests a critical role of the central circadian clock in shaping systemic energy metabolism; and discuss the involvement of endocrine factors, neuropeptides, and the autonomic nervous system in the metabolic functions of the central circadian clock.
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影响因子:
8.2
作者:
Below, J. E.;Gamazon, E. R.;Morrison, J. V.;Konkashbaev, A.;Pluzhnikov, A.;McKeigue, P. M.;Parra, E. J.;Elbein, S. C.;Hallman, D. M.;Nicolae, D. L.;Bell, G. I.;Cruz, M.;Cox, N. J.;Hanis, C. L.
通讯作者:
Hanis, C. L.
影响因子:
16.6
作者:
Barca-Mayo O;Pons-Espinal M;Follert P;Armirotti A;Berdondini L;De Pietri Tonelli D
通讯作者:
De Pietri Tonelli D
影响因子:
64.5
作者:
Balsalobre, A;Damiola, F;Schibler, U
通讯作者:
Schibler, U
DOI:
10.1002/eat.20693
发表时间:
2010-04
期刊:
The International journal of eating disorders
影响因子:
--
作者:
Allison KC;Lundgren JD;O'Reardon JP;Geliebter A;Gluck ME;Vinai P;Mitchell JE;Schenck CH;Howell MJ;Crow SJ;Engel S;Latzer Y;Tzischinsky O;Mahowald MW;Stunkard AJ
通讯作者:
Stunkard AJ
影响因子:
5.3
作者:
Belle, Mino D. C.;Hughes, Alun T. L.;Piggins, Hugh D.
通讯作者:
Piggins, Hugh D.