Evaluation of the clinical value of carbon nanoparticles in endoscopic thyroidectomy and prophylactic central neck dissection through total mammary areolas approach for thyroid cancer.
Evaluation of the clinical value of carbon nanoparticles in endoscopic thyroidectomy and prophylactic central neck dissection through total mammary areolas approach for thyroid cancer.
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DOI：
10.1186/s12957-021-02427-8
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发表时间：
2021-11-04
影响因子：
3.2
通讯作者：
Xia F
中科院分区：
文献类型：
--
作者：
He J;Zhang C;Zhang Z;Xia F
碳纳米颗粒(CNS)是一种示踪剂，用于甲状腺癌(TC)患者的甲状腺手术，以帮助清除淋巴结和保护甲状旁腺。碳纳米颗粒在内窥镜甲状腺切除术和预防性中央颈清扫术(PCND)中的促进作用尚未见报道。比较经全乳晕入路内窥镜下甲状腺手术对甲状旁腺(PG)功能的保护作用及甲状旁腺和中央淋巴结的数目。所有内窥镜甲状腺切除术均顺利完成。在一般特征和手术并发症方面，两组均无差异。在原位或在解剖的中央淋巴组织中发现的上PGs和下PGs的平均数量在两组之间没有差异。CN组单侧CND平均清扫数明显多于对照组。然而，当排除小于5 mm的淋巴结时，收获的淋巴结数量没有差异，转移率极低。在经全乳晕入路的内窥镜甲状腺手术中，碳纳米颗粒不能改善对甲状旁腺，尤其是下腺的保护作用。在内窥镜下预防性单侧CND中，不需要使用CNS来促进淋巴收集。
Carbon nanoparticles (CNs) are tracers used in thyroid surgery of patients with thyroid cancer (TC) to help remove lymph nodes and protect the parathyroid gland. The facilitative effect of carbon nanoparticles in endoscopic thyroidectomy and prophylactic central neck dissection (pCND) has not been reported. The protective effect on parathyroid gland (PG) function and the numbers of identified parathyroid glands and central lymph nodes in endoscopic thyroid surgery through the total mammary areolas approach were compared between the CN and control groups. All endoscopic thyroidectomies were successfully completed. No difference was found in either group regarding the general characteristics or operative complications. The mean number of superior PGs and inferior PGs identified in situ or in the dissected central lymph tissues was not different between the groups. The mean number of lymph nodes removed by unilateral CND was greater in the CN group than in the control group. However, there was no difference in the number of harvested lymph nodes when excluding the LNs less than 5 mm, which exhibit an extremely low metastatic rate. Carbon nanoparticles do not improve the protective effect on the parathyroid gland, especially the inferior glands, in endoscopic thyroid surgery through the total mammary areolas approach. There is no need to use CNs to facilitate the lymph node harvest in endoscopic prophylactic unilateral CND.
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影响因子：
1.6
作者：
Zhao WJ;Luo H;Zhou YM;Gou ZH;Wang B;Zhu JQ
通讯作者：
Zhu JQ
影响因子：
--
作者：
Chen Z;Zhong Z;Chen G;Feng Y
通讯作者：
Feng Y
影响因子：
--
作者：
Rao S;Wang Z;Pan C;Wang Y;Lin Z;Pan Z;Yu J
通讯作者：
Yu J
DOI：
10.1016/j.jss.2021.02.035
发表时间：
2021-08
期刊：
The Journal of surgical research
影响因子：
--
作者：
Dismukes J;Fazendin J;Obiarinze R;Márquez GCH;Ramonell KM;Buczek E;Lindeman B;Chen H
通讯作者：
Chen H
影响因子：
1.8
作者：
Chen, Yijun;Zhang, Guolie;Gao, Jian
通讯作者：
Gao, Jian