CT Angiography or Cardiac MRI for Detection of Coronary Artery Aneurysms in Kawasaki Disease.
CT Angiography or Cardiac MRI for Detection of Coronary Artery Aneurysms in Kawasaki Disease.
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DOI：
10.3389/fped.2021.630462
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发表时间：
2021
影响因子：
2.6
通讯作者：
Kuijpers T
中科院分区：
文献类型：
--
作者：
van Stijn D;Planken N;Kuipers I;Kuijpers T
背景：川崎病(KD)是一种主要累及冠状动脉的急性血管炎。这种炎症可导致冠状动脉动脉瘤(CAA)。KD患者需要进行心脏评估，根据Z-Score(经体表面积校正的冠状动脉内径)对发展为心肌缺血的风险分层。超声心动图是KD的主要成像手段，但有几个重要的局限性。冠状动脉CT血管成像(CCTA)和心脏磁共振成像(CMR)是一种无创的成像方法，对评估CAAS有很高的诊断率。这项单中心回顾性研究的目的是探索CCTA和CMR对KD儿童冠状动脉评估的诊断潜力。方法和结果：自2010年以来，在我们数据库中的965例KD患者中，共进行了111例CCTA(104例)和311例CMR(225例)。为了进行比较，我们确定了54名同时接受过CCTA和CMR的KD患者。CMR只发现了8名CAAS患者，而CCTA发现了14名患者。CMR漏诊了CCTA所确定的CAA的50%。结论：我们的单中心研究表明，与CMR相比，CCTA可能是检测KD患者CAAS的更敏感的诊断工具。
Background: Kawasaki disease (KD) is an acute vasculitis that mainly affects the coronary arteries. This inflammation can cause coronary artery aneurysms (CAAs). Patients with KD need cardiac assessment for risk stratification for the development of myocardial ischemia, based on Z-score (luminal diameter of the coronary artery corrected for body surface area). Echocardiography is the primary imaging modality in KD but has several important limitations. Coronary computed tomographic angiography (cCTA) and Cardiac MRI (CMR) are non-invasive imaging modalities and of additional value for assessment of CAAs with a high diagnostic yield. The objective of this single center, retrospective study is to explore the diagnostic potential of coronary artery assessment of cCTA vs. CMR in children with KD. Methods and Results: Out of 965 KD patients from our database, a total of 111 cCTAs (104 patients) and 311 CMR (225 patients) have been performed since 2010. For comparison, we identified 54 KD patients who had undergone both cCTA and CMR. CMR only identified eight patients with CAAs compared to 14 patients by cCTA. CMR missed 50% of the CAAs identified by cCTA. Conclusions: Our single center study demonstrates that cCTA may be a more sensitive diagnostic tool to detect CAAs in KD patients, compared to CMR.
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影响因子：
1.6
作者：
Dietz SM;Kuipers IM;Koole JCD;Breur JMPJ;Fejzic Z;Frerich S;Dalinghaus M;Roest AAW;Hutten BA;Kuijpers TW
通讯作者：
Kuijpers TW
影响因子：
7.5
作者：
Tacke, Carline E.;Kuipers, Irene M.;Kuijpers, Taco W.
通讯作者：
Kuijpers, Taco W.
影响因子：
3.3
作者：
Fukazawa, Ryuji;Kobayashi, Junjiro;Kimura, Takeshi
通讯作者：
Kimura, Takeshi
影响因子：
37.8
作者：
Nieman, K;Cademartiri, F;de Feyter, PJ
通讯作者：
de Feyter, PJ
影响因子：
4.7
作者：
Nikolaou, Konstantin;Alkadhi, Hatem;Bamberg, Fabian;Leschka, Sebastian;Wintersperger, Bernd J
通讯作者：
Wintersperger, Bernd J