Hemocyanin facilitates lignocellulose digestion by wood-boring marine crustaceans.
Hemocyanin facilitates lignocellulose digestion by wood-boring marine crustaceans.
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DOI:
10.1038/s41467-018-07575-2
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发表时间:
2018-12-03
影响因子:
16.6
通讯作者:
McQueen-Mason SJ
中科院分区:
文献类型:
--
作者:
Besser K;Malyon GP;Eborall WS;Paro da Cunha G;Filgueiras JG;Dowle A;Cruz Garcia L;Page SJ;Dupree R;Kern M;Gomez LD;Li Y;Elias L;Sabbadin F;Mohamad SE;Pesante G;Steele-King C;Ribeiro de Azevedo E;Polikarpov I;Dupree P;Cragg SM;Bruce NC;McQueen-Mason SJ
Woody (lignocellulosic) plant biomass is an abundant renewable feedstock, rich in polysaccharides that are bound into an insoluble fiber composite with lignin. Marine crustacean woodborers of the genus Limnoria are among the few animals that can survive on a diet of this recalcitrant material without relying on gut resident microbiota. Analysis of fecal pellets revealed that Limnoria targets hexose-containing polysaccharides (mainly cellulose, and also glucomannans), corresponding with the abundance of cellulases in their digestive system, but xylans and lignin are largely unconsumed. We show that the limnoriid respiratory protein, hemocyanin, is abundant in the hindgut where wood is digested, that incubation of wood with hemocyanin markedly enhances its digestibility by cellulases, and that it modifies lignin. We propose that this activity of hemocyanins is instrumental to the ability of Limnoria to feed on wood in the absence of gut symbionts. These findings may hold potential for innovations in lignocellulose biorefining. Marine woodborers can digest woody biomass without the help of gut microbiota but the mechanism has remained unclear. Here, the authors provide evidence that the woodborer’s respiratory protein hemocyanin plays a central role in wood digestion and may offer a route toward biorefining of woody plant biomass.
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影响因子:
4.6
作者:
Donaldson L;Vaidya A
通讯作者:
Vaidya A
影响因子:
7.8
作者:
Cragg SM;Beckham GT;Bruce NC;Bugg TD;Distel DL;Dupree P;Etxabe AG;Goodell BS;Jellison J;McGeehan JE;McQueen-Mason SJ;Schnorr K;Walton PH;Watts JE;Zimmer M
通讯作者:
Zimmer M
影响因子:
2.6
作者:
Burmester, Thorsten
通讯作者:
Burmester, Thorsten
DOI:
10.1073/pnas.0805257105
发表时间:
2008-09-02
影响因子:
11.1
作者:
Geib, Scott M.;Filley, Timothy R.;Tien, Ming
通讯作者:
Tien, Ming
影响因子:
56.9
作者:
BOYLE, PJ;MITCHELL, R
通讯作者:
MITCHELL, R