Comparing responsiveness of the EQ-5D-5L, EQ-5D-3L and EQ VAS in stroke patients.
Comparing responsiveness of the EQ-5D-5L, EQ-5D-3L and EQ VAS in stroke patients.
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DOI：
10.1007/s11136-014-0873-7
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发表时间：
2015-06
影响因子：
3.5
通讯作者：
Pickard, A. Simon
中科院分区：
文献类型：
--
作者：
Golicki, Dominik;Niewada, Maciej;Karlinska, Anna;Buczek, Julia;Kobayashi, Adam;Janssen, M. F.;Pickard, A. Simon
To date, evidence to support the construct validity of the EQ-5D-5L has primarily focused on cross-sectional data. The aims of this study were to examine the responsiveness of EQ-5D-5L in patients with stroke and to compare it with responsiveness of EQ-5D-3L and visual analogue scale (EQ VAS). We performed an observational longitudinal cohort study of patients with stroke. At 1 week and 4 months post-stroke, patients were assessed with modified Rankin Scale (mRS) and Barthel Index (BI) and were administered the EQ-5D-5L and EQ-5D-3L, including the EQ VAS. The EQ-5D-5L index scores were derived using the crosswalk methodology developed by the EuroQol Group. We classified patients according to two external criteria, based on mRS or BI, into 3 categories: ‘improvement,’ ‘stable’ or ‘deterioration’. We assessed the responsiveness of each measure in each patient subgroup using: effect size (ES), standardized response mean (SRM), F-statistic, relative efficiency and area under the receiver operating characteristic curve. A total of 112 patients (52 % females; mean age 70.6 years; 93 % ischemic stroke) completed all the instruments at both occasions. In subjects with clinical improvement, EQ-5D-5L was consistently responsive, showing moderate ES (0.51–0.71) and moderate to large SRM (0.69–0.86). In general, EQ-5D-3L index appeared to be more responsive (ES 0.63–0.82; SRM 0.77–1.06) and EQ VAS less responsive (ES 0.51–0.65; SRM 0.59–0.69) than EQ-5D-5L index. The EQ-5D-5L index, based on the crosswalk value set, seems to be appropriately responsive in patients with stroke, 4 months after disease onset. As far as EQ-5D-5L index is scored according to crosswalk approach, the EQ-5D-3L index appears to be more responsive in stroke population.
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影响因子：
4.5
作者：
Golicki, Dominik;Jakubczyk, Michal;Busschbach, Jan J. V.
通讯作者：
Busschbach, Jan J. V.
影响因子：
4.2
作者：
Hsieh, Yu-Wei;Wang, Chun-Hou;Hsieh, Ching-Lin
通讯作者：
Hsieh, Ching-Lin
影响因子：
3.5
作者：
Kim, Seon Ha;Kim, Hwa Jung;Jo, Min-Woo
通讯作者：
Jo, Min-Woo
影响因子：
3.3
作者：
Brooks, R
通讯作者：
Brooks, R
DOI：
10.1682/jrrd.2003.01.0001
发表时间：
2003-01-01
影响因子：
--
作者：
Dromerick, AW;Edwards, DF;Diringer, MN
通讯作者：
Diringer, MN