Incidence of and risk factors for change in urinary incontinence status in a prospective cohort of middle-aged and older women: the reproductive risk of incontinence study in Kaiser.
Incidence of and risk factors for change in urinary incontinence status in a prospective cohort of middle-aged and older women: the reproductive risk of incontinence study in Kaiser.
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DOI：
10.1016/j.juro.2010.05.095
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发表时间：
2010-10
期刊：
影响因子：
--
通讯作者：
Van Den Eeden SK
中科院分区：
文献类型：
--
作者：
Thom DH;Brown JS;Schembri M;Ragins AI;Subak LL;Van Den Eeden SK
尿失禁是一个动态的条件，可以进步和倒退，但很少有研究探讨的风险因素，在失禁状态的变化。采用分层随机抽样的方法，对2109名年龄在40 - 69岁之间的女性进行了一个种族/民族多样化的人群队列研究。通过问卷调查和查阅病历收集数据。第二次调查，大约5年后，完成了1413（67%）的原始队列。尿失禁的频率分为"每周“、”每周“和”每天“。尿失禁状态的变化定义为“新发”尿失禁、频率类别之间的尿失禁“进展”或“消退”以及尿失禁的“消退"。预测变量包括人口统计学、体重指数（BMI）和其他医疗条件。Logistic回归用于估计调整后的比值比（OR）和95%置信区间（95% CI）。与白色、非西班牙裔女性相比，非裔美国女性尿失禁进展的可能性较小（OR= 0.46，95% CI=0.24-0.88）。新发尿失禁在基线时BMI较高的女性中更常见（p=0.006），研究期间BMI增加（p=0.03）或总体健康状况下降（p=0.007）。基线时患有COPD的参与者更有可能报告失禁进展（OR=2.64，95% CI=1.22-5.70）。基线尿失禁类型与独立于频率的排尿状态变化风险无显著相关性。确定尿失禁状态变化的风险因素可能对制定干预措施以减轻普通人群的尿失禁负担非常重要。
Urinary incontinence is a dynamic condition that can progress and regress, but few studies have examined risk factors for change in incontinence status. Stratified random sampling was used to construct a racially/ethnically diverse, population-based cohort of 2109 women age 40 to 69 years old. Data were collected by questionnaires and review of medical records. A second survey, approximately 5 years later, was completed by 1413 (67%) of the original cohort. Frequency of urinary incontinence was categorized as ‘<weekly,’ ‘weekly’ and ‘daily.’ Change in incontinence status was defined as ‘new onset’ incontinence, ‘progression’ or ‘regression ‘of incontinence between frequency categories, and ‘resolution’ of incontinence. Predictor variables included demographics, body mass index (BMI) and other medical conditions. Logistic regression was used to estimate adjusted odds ratios (ORs) and 95% confidence intervals (95% CIs). Compared to white, non-Hispanic women, African-American women were less likely to have progression of incontinence (OR= 0.46, 95% CI=0.24–0.88). New onset of incontinence was more common in women with higher BMI at baseline (p=0.006), who experienced an increase in BMI (p=0.03) or a decline in general health (p=0.007) during the study. Participants with COPD at baseline were more likely to report progression of incontinence (OR=2.64, 95% CI=1.22–5.70). Type of baseline incontinence was not significantly associated with risk of change in continence status independent of frequency. Identifying risk factors for change in incontinence status may be important in developing interventions to reduce the burden of incontinence in the general population.
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影响因子：
7.2
作者：
Townsend, Mary K.;Danforth, Kim N.;Grodstein, Francine
通讯作者：
Grodstein, Francine
影响因子：
9.8
作者：
Samuelsson, EC;Victor, FTA;Svärdsudd, KF
通讯作者：
Svärdsudd, KF
影响因子：
7.2
作者：
Jackson, Sara L.;Scholes, Delia;Fihn, Stephan D.
通讯作者：
Fihn, Stephan D.
影响因子：
7.2
作者：
Rortveit, G;Hannestad, YS;Hunskaar, S
通讯作者：
Hunskaar, S
DOI：
10.1111/j.1532-5415.2008.01747.x
发表时间：
2008-07-01
影响因子：
6.3
作者：
Lifford, Karen L.;Townsend, Mary K.;Grodstein, Francine
通讯作者：
Grodstein, Francine