An inverse approach to identifying the in vivo material parameters of female pelvic floor muscles using MRI data

An inverse approach to identifying the in vivo material parameters of female pelvic floor muscles using MRI data
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利用 MRI 数据识别女性盆底肌肉体内材料参数的逆向方法

DOI:
10.1007/s11427-014-4771-6
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发表时间:
2015-01
期刊:
Science China Life Sciences
影响因子:
--
通讯作者:
Feng Feng
Feng Feng
中科院分区:
其他
文献类型:
--
作者:
Xiang ZhiHai;Chen Cong;Hou Bo;Feng Feng

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骨盆底(PF)功能障碍包括广泛的相互关联的临床条件,并代表一个重要的健康问题。PF支撑系统可以被视为具有复杂几何形状的负载结构,其支持腹压的增加并维持盆腔器官的正常位置(图1A)。人民警察支持系统的弱化被认为是人民警察功能失调的原因。近年来,为了提高对这种结构的生物力学理解,人们尝试用有限元方法来计算其应力分布[1]。PF肌肉材料参数的可靠性对有限元分析至关重要。然而,这些材料参数通常通过体外机械测试来表征,其不同于生理或体内状态下的那些。因此,人们更加关注体内生物力学性能[2]。本文提出了一种非侵入性的逆方法来识别在体材料参数的PF肌肉。这种方法试图提供更符合实际的材料参数,从而对数值模拟有更大的帮助。
Pelvic floor (PF) dysfunctions comprise of a wide spectrum of interrelated clinical conditions and represent an important health problem. The PF supporting system can be regarded as a loaded structure with a complex geometry that supports the increase of abdominal pressure and maintain normal position of pelvic organs (Figure 1A). The weakening of the PF supporting system is considered to be the cause of these PF dysfunctions. Recently, scientists have tried to use the finite element (FE) method to calculate the stress distributions to improve the biomechanical understandings in such structure [1].The reliability of the material parameters of the PF muscles is crucial to the FE analysis. However, these material parameters are conventionally characterized through in vitro mechanical tests, which differ from those in the physiological or in vivo state. Therefore, people pay more attention to the in vivo biomechanical properties [2]. This paper develops a non-invasive inverse approach to identify the in vivo material parameters of the PF muscles. This approach tries to provide more realistic material parameters, thus may give more help to the numerical simula-
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