Shaping vulnerable bodies at the thin boundary between environment and organism : skin, DNA repair, and a genealogy of DNA care strategies
Shaping vulnerable bodies at the thin boundary between environment and organism : skin, DNA repair, and a genealogy of DNA care strategies
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在环境和有机体之间的薄弱边界上塑造脆弱的身体:皮肤、DNA 修复和 DNA 护理策略谱系
DOI:
10.1017/s0269889715000162
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发表时间:
2015
影响因子:
0.3
通讯作者:
Alexander v. Schwerin
中科院分区:
文献类型:
--
作者:
Alexander v. Schwerin
This paper brings together the history of risk and the history of DNA repair, a biological phenomenon that emerged as a research field in between molecular biology, genetics, and radiation research in the 1960s. The case of xeroderma pigmentosum (XP), an inherited hypersensitivity to UV light and, hence, a disposition to skin cancer will be the starting point to argue that, in the 1970s and 1980s, DNA repair became entangled in the creation of new models of the human body at risk – what is here conceptually referred to as the vulnerability aspect of body history – and new attempts at cancer prevention and enhancement of the body associated with the new flourishing research areas of antimutagenesis and anticarcinogenesis. The aim will be to demonstrate that DNA repair created special attempts at disease prevention: molecular enhancement, seeking to identify means to increase the self-repair abilities of the body at the molecular level. Prevention in this sense meant enhancing the body's ability to cope with the environmental hazards of an already toxic world. This strategy has recently been adopted by the beauty industry, which introduced DNA care as a new target for skin care research and anti-aging formulas.
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DOI:
--
发表时间:
2002
期刊:
影响因子:
--
作者:
A. Petersen;R. Bunton
通讯作者:
R. Bunton
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
I. Zweiniger‐Bargielowska
通讯作者:
I. Zweiniger‐Bargielowska
DOI:
10.4324/9781315655819
发表时间:
2010
期刊:
The Journal of Physical Chemistry. C, Nanomaterials and Interfaces
影响因子:
--
作者:
C. Bonah;D. Cantor;M. Dörries
通讯作者:
M. Dörries
DOI:
--
发表时间:
1987
期刊:
Mutation research
影响因子:
--
作者:
R. F. Kimball
通讯作者:
R. F. Kimball
影响因子:
0.8
作者:
Creager, Angela N. H.;Santesmases, Maria Jesus
通讯作者:
Santesmases, Maria Jesus