Bayesian Parametric Accelerated Failure Time Spatial Model and its Application to Prostate Cancer.
Bayesian Parametric Accelerated Failure Time Spatial Model and its Application to Prostate Cancer.
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DOI:
10.1080/02664760903521476
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发表时间:
2011-03
影响因子:
1.5
通讯作者:
Lawson AB
中科院分区:
文献类型:
--
作者:
Zhang J;Lawson AB
Prostate cancer is the most common cancer diagnosed in American men and the second leading cause of death from malignancies. There are large geographical variation and racial disparities existing in the survival rate of prostate cancer. Much work on the spatial survival model is based on the proportional hazards model, but few focused on the accelerated failure time model. In this paper, we investigate the prostate cancer data of Louisiana from the SEER program and the violation of the proportional hazards assumption suggests the spatial survival model based on the accelerated failure time model is more appropriate for this data set. To account for the possible extra-variation, we consider spatially-referenced independent or dependent spatial structures. The deviance information criterion (DIC) is used to select a best fitting model within the Bayesian frame work. The results from our study indicate that age, race, stage and geographical distribution are significant in evaluating prostate cancer survival.
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