Efficient asymmetric synthesis of tryptophan analogues having useful photophysical properties.
Efficient asymmetric synthesis of tryptophan analogues having useful photophysical properties.
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DOI：
10.1021/ol403429e
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发表时间：
2014-01-17
期刊：
影响因子：
5.2
通讯作者：
Hecht, Sidney M.
中科院分区：
文献类型：
--
作者：
Talukder, Poulami;Chen, Shengxi;Arce, Pablo M.;Hecht, Sidney M.
Two new fluorescent probes of protein structure and dynamics have been prepared by concise asymmetric syntheses using the Schöllkopf chiral auxiliary. The site-specific incorporation of one probe into dihydrofolate reductase is reported. The utility of these tryptophan derivatives lies in their absorption and emission maxima which differ from those of tryptophan, as well as in their large Stokes shifts and high molar absorptivities.
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影响因子：
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作者：
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通讯作者：
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