Gene therapy and tissue engineering in orthopaedic surgery.
Gene therapy and tissue engineering in orthopaedic surgery.
复制标题
骨科手术中的基因治疗和组织工程。
DOI：
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发表时间：
2002
影响因子：
3.2
通讯作者：
J. Huard
中科院分区：
文献类型：
--
作者：
D. Musgrave;Freddie H. Fu;J. Huard
A new biologic era of orthopaedic surgery has been initiated by basic scientific advances that have resulted in the development of gene therapy and tissue engineering approaches for treating musculoskeletal disorders. The terminology, fundamental concepts, and current research in this burgeoning field must be understood by practicing orthopaedic surgeons. Different gene therapy approaches, multiple gene vectors, a multitude of cytokines, a growing list of potential scaffolds, and putative stem cells are being studied. Gene therapy and tissue engineering applications for bone healing, articular disorders, intervertebral disk pathology, and skeletal muscle injuries are being explored. Innovative methodologies that ensure patient safety can potentially lead to many new treatment strategies for musculoskeletal conditions.
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影响因子：
3.3
作者：
Kasemkijwattana, C;Menetrey, J;Huard, J
通讯作者：
Huard, J
DOI：
10.2106/00004623-199907000-00002
发表时间：
1999-07-01
影响因子：
5.3
作者：
Lieberman, JR;Daluiski, A;Witte, ON
通讯作者：
Witte, ON
DOI：
10.1073/pnas.93.12.5753
发表时间：
1996-06-11
影响因子：
11.1
作者：
Fang, JM;Zhu, YY;Roessler, BJ
通讯作者：
Roessler, BJ
影响因子：
4.1
作者：
Musgrave, DS;Bosch, P;Huard, J
通讯作者：
Huard, J
DOI：
10.1073/pnas.95.8.4613
发表时间：
1998-04-14
影响因子：
11.1
作者：
Ghivizzani, SC;Lechman, ER;Robbins, PD
通讯作者：
Robbins, PD