Calcium attenuates cardiovascular reactivity to sodium and stress in blacks.
Calcium attenuates cardiovascular reactivity to sodium and stress in blacks.
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钙可以减弱黑人心血管对钠的反应和压力。
DOI：
10.1093/ajh/3.6.451
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发表时间：
1990
影响因子：
3.2
通讯作者：
Francis,RA
中科院分区：
文献类型：
--
作者：
Ernst,FA;Enwonwu,CO;Francis,RA
饮食和行为因素在高血压病因学中的作用尚不清楚。易患高血压被认为受到营养、遗传、神经生理和心理社会影响的复杂相互作用的影响。我们研究了一组29名血压正常的年轻男性的心血管对钠和应激的反应，这些男性由于家族和/或种族因素而易患高血压。父母有阳性和阴性高血压病史的受试者在5天内提供所有膳食，在此期间，在每餐前监测血压。两组分别给予300 mEq/天的膳食钠和1100 mg/天或410 mg/天的膳食钙。第三组食用10 mEq钠饮食，饮食钙低。在饮食的第五天，使用改良的Stroop测试作为精神挑战性任务来测试所有受试者的心血管反应性。收缩压（SBP）从第一至第五早餐的适应是最明显的高钙高钠消费的受试者。高钠低钙饮食者和父母有高血压病史者的SBP对反复精神挑战的反应性持续降低。持续性现象在尿钙排泄量最高的受试者中尤其明显。我们的研究结果表明，膳食钙及其保留对心血管反应性钠和压力的预防性影响。我们还阐明了一个理论命题的作用，神经生理抑制能力的过渡，从正常紧张的慢性失调状态的原发性高血压。美国高血压杂志1990;3：451-457
The roles of dietary and behavioral factors in the etiology of hypertension are not well understood. Vulnerability to hypertension is thought to be affected by a complex interaction of nutritional, genetic, neurophysiological, and psychosocial influences. We studied cardiovascular reactivity to sodium and stress in a group of 29 normotensive young men who were vulnerable to hypertension by virtue of familial and/or racial factors. Subjects with positive and negative parental histories of hypertension were provided all meals for five days during which blood pressure was monitored before each meal. Two groups were given 300 mEq/day dietary sodium with either 1100 mg/day or 410 mg/day dietary calcium. A third group consumed a lOmEq sodium diet with low dietary calcium. On the fifth day of the diet all subjects were tested for cardiovascular reactivity using a modified Stroop test as a mentally challenging task. Adaptation of systolic blood pressure (SBP) from the first to the fifth breakfast was most pronounced in subjects consuming high calcium with high sodium. Perse-veration of SBP reactivity to repeated mental challenge was found in subjects who consumed high sodium with low calcium and in subjects with positive parental histories of hypertension. The perseverative phenomenon was particularly well-defined in subjects who had the highest urinary excretion of calcium. Our findings suggest a prophylactic influence of dietary calcium and its retention on cardiovascular reactivity to sodium and stress. We also elucidate a theoretical proposition concerning the role of neurophysiological inhibitory capacity in the transition from normo-tension to the chronic dysregulatory state of essential hypertension. Am J Hypertens 1990;3:451-457
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男同性恋者的机会性感染和免疫缺陷。
影响因子：
39.2
作者：
D. Mildvan;U. Mathur;R. Enlow;P. L. Romain;R. Winchester;C. Colp;H. Singman;B. Adelsberg;I. Spigland
通讯作者：
I. Spigland
银屑病关节炎和赖特综合征。
影响因子：
4.2
作者：
E. P. Engleman
通讯作者：
E. P. Engleman
影响因子：
--
作者：
O. Broch
通讯作者：
O. Broch
艾滋病会加剧牛皮癣。
DOI：
10.1056/nejm198511283132210
发表时间：
1985
期刊：
The New England journal of medicine
影响因子：
--
作者：
Timothy M. Johnson;Madeleine Duvic;Ronald P. Rapini;Adan Rios
通讯作者：
Adan Rios
不完全赖特综合征：诊断中的鉴别特征和 HL-A W27。
影响因子：
39.2
作者：
F. Arnett;O. E. McClusky;B. Schacter;R. Lordon
通讯作者：
R. Lordon