Cerebral Metabolic and Vasopressin and Oxytocin Responses During Osmotic Stimulation in Conscious Rats
Cerebral Metabolic and Vasopressin and Oxytocin Responses During Osmotic Stimulation in Conscious Rats
复制标题
清醒大鼠渗透刺激期间的脑代谢以及加压素和催产素反应
DOI：
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发表时间：
1992
影响因子：
3.2
通讯作者：
H. Eisenberg
中科院分区：
文献类型：
--
作者：
M. Kadekaro;J. Summy;J. Harris;M. L. Terrell;S. Freeman;H. Eisenberg
静脉输注高渗盐水可增加血浆[Na +]和渗透压摩尔浓度，并诱导短潜伏期饮水反应。这些变化与视上核和室旁核和神经叶的葡萄糖利用增加以及内侧隔和疑核的葡萄糖利用减少有关。葡萄糖利用率的增加在视上核比室旁核更明显，表明它们比室旁核对渗透刺激更敏感。与下丘脑-神经垂体系统的活动增强相关，血浆加压素和催产素浓度增加，催产素的优先增加超过加压素。神经叶中的激素含量并没有耗尽的渗透刺激，尽管它们在血浆中的浓度大幅增加。
Intravenous infusion of hypertonic saline increased plasma [Na +] and osmolality and induced a short‐latency drinking response. These changes were associated with increased glucose utilization in the supraoptic and paraventricular nuclei and neural lobe, and decreases in the medial septum and nucleus ambiguus. The increases in glucose utilization were more accentuated in the supraoptic nuclei than in paraventricular nuclei, indicating that they are more sensitive to osmotic stimulation than the paraventricular nuclei. In association with enhanced activity in the hypothalamo‐neurohypophysial system, plasma vasopressin and oxytocin concentrations increased, with a preferential increase of oxytocin over vasopressin. The hormonal contents in the neural lobe were not depleted by the osmotic stimulus despite the large increases of their concentrations in the plasma.
影响因子：
4.8
作者：
T. Thrasher;L. Keil;D. Ramsay
通讯作者：
T. Thrasher;L. Keil;D. Ramsay
影响因子：
4.8
作者：
VERBALIS, JG;MANGIONE, MP;STRICKER, EM
通讯作者：
STRICKER, EM
大鼠进行性缺水期间的脑代谢反应以及加压素和催产素分泌。
DOI：
10.1152/ajpregu.1992.262.2.r310
发表时间：
1992
期刊：
The American journal of physiology
影响因子：
--
作者：
Kadekaro,M;Summy-Long,JY;Freeman,S;Harris,JS;Terrell,ML;Eisenberg,HM
通讯作者：
Eisenberg,HM