Combined corticospinal and reticulospinal effects on upper limb muscles.

Combined corticospinal and reticulospinal effects on upper limb muscles.
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DOI:
10.1016/j.neulet.2013.12.043
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发表时间:
2014-02-21
影响因子:
2.5
通讯作者:
Buford JA
Buford JA
中科院分区:
医学4区
文献类型:
--
作者:
Ortiz-Rosario A;Berrios-Torres I;Adeli H;Buford JA

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已知网状脊髓系统和皮质脊髓系统都控制上肢肌肉的募集,但没有已知的研究试图在清醒的行为灵长类动物的同一实验中评估它们的联合作用。本研究的目的是提出一种分析这两个电机系统协同控制的方法。研究了网状脊髓系统和皮质脊髓系统单独或组合对电刺激的肌肉反应。这些反应是根据简单的神经回路进行分类的,这些神经回路可以解释这些系统的相互作用。确定了五个这样的电路,可以解释86%的观察到的模式,在刺激过程中的组合招聘。对这些运动系统之间合作的更好理解可以为中风患者和其他运动障碍患者开发更好的康复方法提供见解。
Both the reticulospinal and corticospinal systems are known to control recruitment of upper limb muscles, yet no known studies have attempted to assess their combined effects in the same experiment in the awake, behaving primate. The purpose of this study is to present an approach for the analysis of the cooperative control from these two motor systems. Muscle responses to electrical stimulation in the reticulospinal system and corticospinal system alone or in combination were studied. The responses were categorized based on simple neural circuits that could explain the interactions of these systems. Five such circuits were identified that could explain 86% of the observed patterns of combined recruitment during stimulation. Improved understanding of the cooperation between these motor systems could provide insight for development of better rehabilitation approaches for stroke patients and others with movement disorders.
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