Ambient mass spectrometry: Approaching the chemical analysis of things as they are
Ambient mass spectrometry: Approaching the chemical analysis of things as they are
复制标题
环境质谱：对事物进行化学分析
DOI：
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发表时间：
2011
期刊：
影响因子：
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通讯作者：
G. Hieftje
中科院分区：
文献类型：
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作者：
J. Shelley;G. Hieftje
作为G.E.F.伦德尔曾经指出，分析科学的目标是提供对事物的化学分析;然而，在分析技术的发展，特别是在使用中，这一概念往往被忽视。环境解吸/电离质谱领域试图通过对未处理样品进行直接、灵敏和选择性分析来扭转这一趋势。由于这种能力，自2004年引入以来，该领域受到了极大的关注。事实上，这种反应似乎遵循了一个炒作周期模型，在这个模型中，我们目前正处于膨胀的期望的顶峰。为了减少负面宣传（即幻灭的低谷）的影响，这可能会破坏该领域，必须花费更多的努力从根本上了解环境质谱分析所涉及的过程。这里引用的例子来说明基于等离子体的环境解吸/电离的局限性和基础研究，努力评估该领域的当前状态。
As G.E.F. Lundell once indicated, the goal of the analytical sciences is to provide the chemical analysis of things as they are; however, this concept is often ignored in the development, and especially in the use, of analytical techniques. The field of ambient desorption/ionization mass spectrometry seeks to reverse this trend by enabling direct, sensitive, and selective analysis of untreated samples. Because of this ability, significant interest has surrounded the field since its introduction in 2004. In fact, the response seems to follow a Hype Cycle model, in which we are currently at the peak of inflated expectations. To lessen the impact of negative hype (i.e. the trough of disillusionment), which could destroy the field, more effort must be expended on fundamentally understanding the processes involved in ambient mass-spectrometric analyses. Examples are cited here to illustrate the limitations of and fundamental research on plasma-based ambient desorption/ionization in an effort to evaluate the current state of the field.
影响因子：
4.2
作者：
Kauppila, Tiina J.;Talaty, Nari;Cooks, R. Graham
通讯作者：
Cooks, R. Graham
影响因子：
7.4
作者：
Shelley, Jacob T.;Wiley, Joshua S.;Hieftje, Gary M.
通讯作者：
Hieftje, Gary M.