Current and emerging technologies in melanoma diagnosis: the state of the art.

Current and emerging technologies in melanoma diagnosis: the state of the art.
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DOI:
10.1016/j.clindermatol.2008.09.004
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发表时间:
2009-01
影响因子:
2.7
通讯作者:
Halpern AC
Halpern AC
中科院分区:
医学3区
文献类型:
--
作者:
Psaty EL;Halpern AC

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与其他专业相比,皮肤科医生在采用先进技术诊断辅助工具方面进展缓慢。毕竟,大多数皮肤病可以通过简单的目视检查来诊断,并且可以轻松地对皮肤进行诊断性活检。然而,全身摄影和皮肤镜检查等诊断辅助手段提高了临床医生诊断黑色素瘤的能力,超出了肉眼检查的范围,现在被认为是早期检测的主流方法。目前正在研究体内反射共焦显微镜等新兴技术,以确定其在黑色素瘤无创诊断中的效用。本综述总结了当前可用的皮肤成像设备和皮肤病无创诊断的新领域。我们预计,结合不同成像技术的多模态系统将进一步提高我们在床边早期检测黑色素瘤的能力。
Relative to other specialties, dermatologists have been slow to adopt advanced technologic diagnostic aids. After all, most skin disease can be diagnosed by simple visual inspection, and the skin is readily accessible for a diagnostic biopsy. Diagnostic aids such as total body photography and dermoscopy improve the clinician's ability to diagnose melanoma beyond unaided visual inspection, however, and are now considered mainstream methods for early detection. Emerging technologies such as in vivo reflectance confocal microscopy are currently being investigated to determine their utility for noninvasive diagnosis of melanoma. This review summarizes the currently available cutaneous imaging devices and new frontiers in noninvasive diagnosis of skin disease. We anticipate that multimodal systems that combine different imaging technologies will further improve our ability to detect, at the bedside, melanoma at an earlier stage.
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