'When will this end? Will it end?' The impact of the March-June 2020 UK COVID-19 lockdown response on mental health: a longitudinal survey of mothers in the Born in Bradford study.

'When will this end? Will it end?' The impact of the March-June 2020 UK COVID-19 lockdown response on mental health: a longitudinal survey of mothers in the Born in Bradford study.
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DOI:
10.1136/bmjopen-2020-047748
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发表时间:
2022-01-11
期刊:
影响因子:
2.9
通讯作者:
Bradford Institute for Health Research Covid-19 Scientific Advisory Group
Bradford Institute for Health Research Covid-19 Scientific Advisory Group
中科院分区:
医学3区
文献类型:
--
作者:
Dickerson J;Kelly B;Lockyer B;Bridges S;Cartwright C;Willan K;Shire K;Crossley K;Bryant M;Siddiqi N;Sheldon TA;Lawlor DA;Wright J;McEachan RR;Pickett KE;Bradford Institute for Health Research COVID-19 Scientific Advisory Group;Bradford Institute for Health Research Covid-19 Scientific Advisory Group

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探索从英国首次COVID-19封锁之前到期间抑郁/焦虑的临床重要增加,以及与这一变化相关的因素,特别关注种族差异。在布拉德福德出生的两项纵向队列研究中嵌套的covid -19前和封锁调查。1860名母亲带着0-5岁或9-13岁的孩子,48%是巴基斯坦血统。在未调整的回归分析中,抑郁(8项患者健康问卷(PHQ-8))和焦虑(广广性焦虑障碍评估(GAD-7))的临床重要增加(5分或以上)的ORs,重复使用按种族分开的感兴趣暴露,以寻找关联程度的差异,以及在开放文本问题中获取的母亲的生活经历。报告临床重要抑郁/焦虑的妇女人数分别从11%增加到20% (95% CI 10% - 13%; 18%-22%)和从10%增加到16% (95% CI 8%-11%; 15%-18%)。抑郁/焦虑的增加与孤独感相关(OR=8.37, 95% CI 5.70 ~ 12.27; OR= 8.50, 95% CI 5.71 ~ 12.65);金融(6.23,95% CI 3.96 - 9.80; 6.03, 95% CI 3.82 - 9.51),食品(3.33,95% CI 2.09 - 5.28; 3.46, 95% CI 2.15 - 5.58)和住房不安全(3.29,95% CI 2.36 - 4.58; 3.0, 95% CI 2.11 - 4.25);缺乏身体活动(3.13,95%可信区间2.15 - 4.56;2.55,95%可信区间1.72 - 3.78);和不良的伴侣关系(3.6,95% CI 2.44 ~ 5.43; 5.1, 95% CI 3.37 ~ 7.62)。关键暴露与心理健康恶化之间的关联程度因种族而异。对开放式文本问题的回答说明了导致精神疾病的各种挑战的复杂相互作用,包括:急性健康焦虑;管理多重责任的精神负担;失去社会支持和应对策略;财政和就业不安全的压力;而且无法摆脱大流行。在COVID-19封锁期间,许多人的心理健康状况恶化,特别是那些孤独和经济不安全的人。关键暴露与心理健康恶化之间的关联程度因种族而异。精神健康问题可能对公共卫生产生长期影响,需要采取措施解决潜在原因。
To explore clinically important increases in depression/anxiety from before to during the first UK COVID-19 lockdown and factors related to this change, with a particular focus on ethnic differences. Pre-COVID-19 and lockdown surveys nested within two longitudinal Born in Bradford cohort studies. 1860 mothers with a child aged 0–5 or 9–13, 48% Pakistani heritage. ORs for a clinically important increase (5 points or more) in depression (eight item Patient Health Questionnaire (PHQ-8)) and anxiety (Generalised Anxiety Disorder Assessment (GAD-7)) in unadjusted regression analyses, repeated with exposures of interest separated by ethnicity to look for differences in magnitude of associations, and lived experience of mothers captured in open text questions. The number of women reporting clinically important depression/anxiety increased from 11% to 20% (95% CI 10%–13%; 18%–22%) and from 10% to 16% (95% CI 8%–11%; 15%–18%), respectively. Increases in depression/anxiety were associated with loneliness (OR=8.37, 95% CI 5.70 to 12.27; 8.50, 95% CI 5.71 to 12.65, respectively); financial (6.23, 95% CI 3.96 to 9.80; 6.03, 95% CI 3.82 to 9.51), food (3.33, 95% CI 2.09 to 5.28; 3.46, 95% CI 2.15 to 5.58) and housing insecurity (3.29, 95% CI 2.36 to 4.58; 3.0, 95% CI 2.11 to 4.25); a lack of physical activity (3.13, 95% CI 2.15 to 4.56; 2.55, 95% CI 1.72 to 3.78); and a poor partner relationship (3.6, 95% CI 2.44 to 5.43; 5.1, 95% CI 3.37 to 7.62). The magnitude of associations between key exposures and worsening mental health varied between ethnic groups. Responses to open text questions illustrated a complex interplay of challenges contributing to mental ill health including: acute health anxieties; the mental load of managing multiple responsibilities; loss of social support and coping strategies; pressures of financial and employment insecurity; and being unable to switch off from the pandemic. Mental ill health has worsened for many during the COVID-19 lockdown, particularly in those who are lonely and economically insecure. The magnitude of associations between key exposures and worsening mental health varied between ethnic groups. Mental health problems may have longer term consequences for public health and interventions that address the potential causes are needed.
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