Population genetics as a tool to select tsetse control strategies: suppression or eradication of Glossina palpalis gambiensis in the Niayes of Senegal.
Population genetics as a tool to select tsetse control strategies: suppression or eradication of Glossina palpalis gambiensis in the Niayes of Senegal.
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DOI：
10.1371/journal.pntd.0000692
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发表时间：
2010-05-25
影响因子：
3.8
通讯作者：
Bouyer J
中科院分区：
文献类型：
--
作者：
Solano P;Kaba D;Ravel S;Dyer NA;Sall B;Vreysen MJ;Seck MT;Darbyshir H;Gardes L;Donnelly MJ;De Meeûs T;Bouyer J
塞内加尔政府启动了“Projet de lutte contre les gllossines dans les Niayes”，以可持续的方式消除该地区的锥虫病问题。由于过去未能从尼亚耶斯地区可持续地根除冈比亚须舌蝇，因此对于最佳策略的实施（即“根除”与“抑制”）仍存在争议。为了为这场争论提供信息，我们利用群体遗传学来测量尼亚耶斯冈比亚须蝇和南部采采带（米西拉）的须蝇之间的遗传分化。对 153 个个体使用了三种不同的标记（微卫星 DNA、线粒体 CO1 DNA 和翅膀的几何形态测量），结果表明 G. p.尼亚耶斯冈比亚种群是从距离最近的已知米西拉种群进行基因分离的。这两个区域之间测量的遗传分化（使用微卫星θ = 0.12）相当于类群之间的分化。我们还证明，在尼亚耶斯地区，来自达喀尔-汉恩的人口与其他人口隔离，并且可能经历了瓶颈。本文提供的信息导致建议对尼亚耶斯种群采取根除战略。这种研究可以在其他栖息地和其他采采蝇物种中重复进行，以（i）帮助决定适当的采采蝇控制策略，以及（ii）找到采采蝇分布中其他可能的不连续性。采采蝇将锥虫传播给人类（昏睡病）和动物（那加那病）。控制这些媒介是遏制这些疾病的非常有效的方法。有多种可用于控制的策略和方法，每种策略和方法的效率或多或少取决于多种因素。塞内加尔政府希望通过控制采采蝇媒介 Glossina palpalis gambiensis，可持续消除尼亚耶斯地区的锥虫病。为了实现这一目标，可以使用两种不同的策略：抑制（减少采采蝇密度）或根除（清除该地区的所有采采蝇，直到最后一个）。为了根除害虫，该方法必须是全区域性的，即控制工作针对限定区域内的整个害虫种群，以避免任何可能的重新入侵。使用了三种不同的工具（微卫星 DNA、线粒体 DNA 和形态计量学），所有工具都显示 G. p. 之间不存在基因流。冈比亚人来自尼亚耶斯和该国东南部最近的已知种群（米西拉）。目标人群的这种基因隔离导致建议对尼亚耶斯人群采取根除策略。这种研究可以扩展到其他领域的其他采采蝇物种。
The Government of Senegal has initiated the “Projet de lutte contre les glossines dans les Niayes” to remove the trypanosomosis problem from this area in a sustainable way. Due to past failures to sustainably eradicate Glossina palpalis gambiensis from the Niayes area, controversies remain as to the best strategy implement, i.e. “eradication” versus “suppression.” To inform this debate, we used population genetics to measure genetic differentiation between G. palpalis gambiensis from the Niayes and those from the southern tsetse belt (Missira). Three different markers (microsatellite DNA, mitochondrial CO1 DNA, and geometric morphometrics of the wings) were used on 153 individuals and revealed that the G. p. gambiensis populations of the Niayes were genetically isolated from the nearest proximate known population of Missira. The genetic differentiation measured between these two areas (θ = 0.12 using microsatellites) was equivalent to a between-taxa differentiation. We also demonstrated that within the Niayes, the population from Dakar – Hann was isolated from the others and had probably experienced a bottleneck. The information presented in this paper leads to the recommendation that an eradication strategy for the Niayes populations is advisable. This kind of study may be repeated in other habitats and for other tsetse species to (i) help decision on appropriate tsetse control strategies and (ii) find other possible discontinuities in tsetse distribution. Tsetse flies transmit trypanosomes to humans (sleeping sickness) and animals (nagana). Controlling these vectors is a very efficient way to contain these diseases. There are several strategies and methods that can be used for control, each being more or less efficient depending on several factors. The Government of Senegal wants to sustainably eliminate trypanosomosis from the Niayes region by controlling the tsetse vector, Glossina palpalis gambiensis. To reach this objective, two different strategies may be used: suppression (decrease in tsetse densities) or eradication (remove all the tsetse in the region until last one). For eradication, the approach has to be area-wide, i.e. the control effort targets an entire pest population within a circumscribed area, to avoid any possible reinvasion. Three different tools (microsatellite DNA, mitochondrial DNA and morphometrics) were used, and all showed an absence of gene flow between G. p. gambiensis from the Niayes and from the nearest known population in the south east of the country (Missira). This genetic isolation of the target population leads to the recommendation that an eradication strategy for the Niayes populations is advisable. This kind of study may be extended to other areas on other tsetse species.
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影响因子：
4.9
作者：
Clement, M;Posada, D;Crandall, KA
通讯作者：
Crandall, KA
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