Effect of soft diet and aging on rat masseter muscle and its motoneuron
Effect of soft diet and aging on rat masseter muscle and its motoneuron
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软食和衰老对大鼠咬肌及其运动神经元的影响
DOI：
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发表时间：
1993
期刊：
影响因子：
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通讯作者：
Y. Shigenaga
中科院分区：
文献类型：
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作者：
H. Miyata;T. Sugiura;Y. Kawai;Y. Shigenaga
为了确定软饮食和衰老对咀嚼运动单位的影响，我们研究了大鼠浅表咬肌及其运动神经元的形态和代谢特性。将 20 只大鼠分为四组，每组 5 只：大鼠在出生后 4 个月之前喂硬饮食（硬，年轻），大鼠在出生后 4 个月之前喂软饮食（软，年轻），大鼠在出生后 22 个月之前喂硬饮食（硬，老年），大鼠在出生后 22 个月之前喂软饮食（软，老年）。软组的快肌氧化糖酵解肌纤维直径显着小于硬组，老年组的快肌纤维直径显着小于年轻组。老年人肌肉的糖酵解酶（磷酸果糖激酶）活性明显弱于年轻组。软、硬组运动神经元体直径无显着差异，而老年组运动神经元体直径显着大于年轻组。软组和硬组运动神经元的 NADH 心肌酶活性没有显着差异，而老年组的活性明显低于年轻组。软饮食引起的运动单位活动减少被认为影响浅层咬肌的形态和代谢特性，但不影响其运动神经元。无论运动单位活性是否降低，运动神经元的氧化酶活性都会随着衰老而降低。 © 1993 Wiley-Liss, Inc.
To determine the effect of a soft diet and aging on the masticatory motor unit, we investigated the morphologic and metabolic properties of the superficial masseter muscle and its motoneurons in rats. Twenty rats were divided into four groups of five rats: rats fed a hard diet until 4 months after birth (hard, young), rats fed a soft diet until 4 months after birth (soft, young), rats fed a hard diet until 22 months after birth (hard, old), and rats fed a soft diet until 22 months after birth (soft, old). The diameter of the fast‐twitch oxidative glycolytic muscle fiber was significantly smaller in the soft than the hard, and in the old than the young groups. The glycolytic enzyme (phosphofructokinase) activity of the muscle was significantly weaker in the old than the young group. There was no significant difference in soma diameter of the motoneurons between the soft and hard group, while the diameter was significantly larger in the old than in the young group. There was no significant difference in NADH‐diaphorase activity of the motoneurons between the soft and hard group, while significantly less activity was demonstrated in the old than in the young group. The reduction in motor unit activity caused by the soft diet is considered to influence the morphologic and metabolic properties in the superficial masseter muscle but not in its motoneurons. The reduction in the oxidative enzyme activity of motoneurons with aging may occur regardless of the reduction in motor unit activity. © 1993 Wiley‐Liss, Inc.
影响因子：
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作者：
ARMSTRONG, RB;PHELPS, RO
通讯作者：
PHELPS, RO