Orthogonal Multifunctionalization of Random and Alternating Copolymers.
Orthogonal Multifunctionalization of Random and Alternating Copolymers.
复制标题
无规和交替共聚物的正交多功能化。
DOI：
10.1021/mz300428n
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发表时间：
2012
影响因子：
7.015
通讯作者：
M. Weck
中科院分区：
文献类型：
--
作者：
N. Ten Brummelhuis;M. Weck
以2，3，4，5，6-五氟苯乙烯（PFS）和含炔丙基的苯乙烯衍生物为原料，通过自由基聚合合成了一系列具有不同交替程度的共聚物。交替的程度随苯乙烯衍生物的电子性质而变化：使用具有吸电子部分的单体获得无规共聚物，而通过增加取代基的供电子性质获得越来越多的交替共聚物。共聚物可以以正交的方式使用亲核取代（与硫醇）官能化PFS和铜催化的叠氮化物和炔丙基基团的炔之间的3 + 2环加成来官能化。这种方法允许官能交替共聚物的简易合成。
A series of copolymers with varying degrees of alternation are synthesized by free-radical polymerization from 2,3,4,5,6-pentafluorostyrene (PFS) and propargyl-containing styrene derivatives. The degree of alternation varied with the electronic nature of the styrene derivative: random copolymers were obtained using monomers with electron withdrawing moieties, whereas increasingly alternating copolymers were obtained by increasing the electron donating nature of the substituent. The copolymers could be functionalized in an orthogonal fashion using a nucleophilic substitution (with thiols) to functionalize PFS and the copper-catalyzed 3 + 2 cycloaddition between azides and the alkyne of the propargyl groups. This methodology allows for the facile synthesis of functional alternating copolymers.
影响因子：
62.1
作者：
Iha RK;Wooley KL;Nyström AM;Burke DJ;Kade MJ;Hawker CJ
通讯作者：
Hawker CJ